ReviewMedicina (Kaunas, Lithuania)2023
Endothelial Dysfunction and Metabolic Disorders in Patients with Sudden Sensorineural Hearing Loss.
Review in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Trends and mechanistic insights into hypertension-associated hearing loss: a 20-year perspective (2005-2025).Frontiers in molecular neuroscience · 2026Pooled it
- Audiovestibular symptoms in systemic sclerosis: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Pooled it
- Association between hearing loss, tinnitus, and atherosclerotic cardiovascular disease among American adults: A cross-sectional study.Medicine · 2026Article
- Association Between Air Pollution and Sudden Sensorineural Hearing Loss: A Nine-Year Retrospective Study.Journal of clinical medicine · 2026Article
- Article
- Study on the relationship between coagulation function, homocysteine, serum oxidative stress and sudden deafness and its clinical implications.Scientific reports · 2026Article
- Microcirculatory Dysfunction and Oxidative Stress in Sudden Sensorineural Hearing Loss: Insights From a Case-Control and Experimental Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- The Potential Impact of Serum Sodium and Potassium Levels on Sensorineural Hearing Loss and Tinnitus.Journal of clinical medicine · 2026Article
- Cardiovascular and sociodemographic factors associated with self-reported hearing loss: a cross-sectional analysis from the Polish PURE cohort.Archives of public health = Archives belges de sante publique · 2026Article
- An explainable machine learning model for prognosis prediction in sudden sensorineural hearing loss under integrated therapy.Frontiers in medicine · 2026Article
- Multimodal biomarkers in idiopathic sudden sensorineural hearing loss: integrating immune, vascular, and metabolic perspectives for precision medicine.Frontiers in immunology · 2026Review
- Association of hearing loss with cardiovascular and mortality risk in the general population.Scientific reports · 2025Article
- Anterior Ischemic Optic Neuropathy as a Paraneoplastic Manifestation of Colorectal Cancer.Cureus · 2025Article
- Clinical efficacy of postauricular injection of Methylprednisolone in the treatment of patients with sudden deafness: A retrospective study.Pakistan journal of medical sciences · 2025Article
- Association between hearing loss and insulin resistance as measured by metabolic score for insulin resistance in NHANES 1999 to 2018.Scientific reports · 2025Article
- Interplay Between Vestibular Dysfunction and Sleep Disorders.Current medical science · 2025Review
- Exploring Endothelial Cell Dysfunction's Impact on the Brain-Retina Microenvironment Connection: Molecular Mechanisms and Implications.Molecular neurobiology · 2025Review
- Therapeutic effectiveness of intratympanic and retroauricular methylprednisolone sodium succinate for refractory sudden sensorineural hearing loss in diabetic patients.World journal of diabetes · 2025Article
- Identification of Risk Loci for Radiotherapy-Induced Tinnitus and Hearing Loss Through Integrated Genomic Analysis.International journal of molecular sciences · 2025Article
- Analysis of genetic polymorphisms in sudden sensorineural hearing loss and artificial intelligence-supported individualized precision therapy.Frontiers in neurology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sudden sensorineural hearing loss (SSNHL) is defined as a sensorineural hearing loss of 30 dB or greater on at least three contiguous audiometric frequencies occurring within a 72 h period. Although SSNHL is commonly encountered in clinical audiology and otolaryngology practice, its etiopathogenesis continues to be poorly understood. Scientific investigations have highlighted the vulnerability of cochlear microcirculation to blood flow alterations. Even mild hypoperfusion can lead to immediate dysfunction in the organ of Corti, given the heightened susceptibility of cochlear hair cells to hypoxia and ischemic damage. The purpose of this review paper is to present evidence of endothelial and vascular involvement in SSNHL and the risk factors, such as metabolic syndrome, that may negatively impact the inner ear's vascular supply, influencing the onset pattern, incidence, and prognosis of SSNHL. By addressing these variables, we can deepen our comprehension of the mechanisms underlying SSNHL and potentially uncover strategies for prevention.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.