Evidence map›Paper›PMID 37894521›Full record

ArticleMolecules (Basel, Switzerland)2023

Multi-Omics Elucidates Difference in Accumulation of Bioactive Constituents in Licorice (

Chengcheng Wang, Dawei Wu, Liying Jiang, Xunhong Liu, Tiantian Xie

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chengcheng WangSchool of Traditional Chinese Medicine, Jiangsu Vocational College of Medicine, Yancheng 224000, China.
Dawei WuSchool of Traditional Chinese Medicine, Jiangsu Vocational College of Medicine, Yancheng 224000, China.
Liying JiangSchool of Traditional Chinese Medicine, Jiangsu Vocational College of Medicine, Yancheng 224000, China.
Xunhong LiuSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Tiantian XieSchool of Traditional Chinese Medicine, Jiangsu Vocational College of Medicine, Yancheng 224000, China.
Jiangsu Vocational College of Medicine · CNNanjing University of Chinese Medicine · CN

Funding

Jiangsu Health Commission Z2021013
6 · The paper itself

Abstract

Licorice is a frequently applied herb with potential edible and medicinal value based on various flavonoids and triterpenes. However, studies on detailed flavonoid and triterpene metabolism and the molecular basis of their biosynthesis in licorice are very limited, especially under drought conditions. In the present study, we carried out transcriptome, proteome, and metabolome experiments. To ultimately combine three omics for analysis, we performed a bioinformatics comparison, integrating transcriptome data and proteome data through a Cloud platform, along with a simplified biosynthesis of primary flavonoids and triterpenoids in the KEGG pathway based on metabolomic results. The biosynthesis pathways of triterpenes and flavonoids are enriched at both gene and protein levels. Key flavonoid-related genes (

Indexed as

GlycyrrhizaGlycyrrhiza uralensisDroughtsFlavonoidsGene Expression Regulation, PlantGlycyrrhizic AcidMultiomicsPlant BreedingProteomeTranscriptomeFlavonoidsGlycyrrhizic AcidProteomebioactive constituentsdrought stressGlycyrrhiza uralensismulti-omics

Identifiers

PMID37894521
PMCPMC10609028
OpenAlexW4387575958

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.