Evidence map›Paper›PMID 37894869›Full record

ArticleInternational journal of molecular sciences2023

Neurolysin Knockout Mice in a Diet-Induced Obesity Model.

Bruna Caprioli, Rosangela A S Eichler, Renée N O Silva, Luiz Felipe Martucci, Patricia Reckziegel, Emer S Ferro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bruna CaprioliPharmacology Department, Biomedical Sciences Institute (ICB), São Paulo 05508-000, SP, Brazil.
Rosangela A S EichlerPharmacology Department, Biomedical Sciences Institute (ICB), São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-7629-0089
Renée N O SilvaPharmacology Department, Biomedical Sciences Institute (ICB), São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-9068-6207
Luiz Felipe MartucciPharmacology Department, Biomedical Sciences Institute (ICB), São Paulo 05508-000, SP, Brazil.
Patricia ReckziegelDepartment of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences (FCF), University of São Paulo (USP), São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-8145-6127
Emer S FerroPharmacology Department, Biomedical Sciences Institute (ICB), São Paulo 05508-000, SP, Brazil.ORCID 0000-0003-1651-9192
Universidade de São Paulo · BR

Funding

São Paulo Research Foundation 2016/04000-3
6 · The paper itself

Abstract

Neurolysin oligopeptidase (E.C.3.4.24.16; Nln), a member of the zinc metallopeptidase M3 family, was first identified in rat brain synaptic membranes hydrolyzing neurotensin at the Pro-Tyr peptide bond. The previous development of C57BL6/N mice with suppression of Nln gene expression (Nln

Indexed as

DietObesityAnimalsFemaleMaleMetalloendopeptidasesMiceMice, KnockoutRatsMetalloendopeptidasesneurolysinadipose tissuediet-induced obesityglucagon-like peptide-1intracellular peptidesleptinneurolysinneurotensinobesity

Identifiers

PMID37894869
PMCPMC10607720
OpenAlexW4387638679

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.