Evidence map›Paper›PMID 37894972›Full record

SynthesisInternational journal of molecular sciences2023

The Role of Carbon Nanoparticles as Lymph Node Tracers in Colorectal Cancer: A Systematic Review and Meta-Analysis.

Georgios Koimtzis, Georgios Geropoulos, Leandros Stefanopoulos, Christopher Gwydion Chalklin, Ioannis Karniadakis, Vyron Alexandrou, Nikos Tteralli, Eliot Carrington-Windo, Andreas Papacharalampous, Kyriakos Psarras

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Efficacy of Nano-Carbon Tracing Versus Indocyanine Green in Lymph Node Detection for Minimally Invasive Colorectal Resection.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Georgios KoimtzisDepartment of General Surgery, University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff CF14 4XW, UK.
Georgios GeropoulosWestern General Hospital, NHS Lothian, Crewe Road South, Edinburgh EH4 2XU, UK.
Leandros StefanopoulosDepartment of Electrical and Computer Engineering, Northwestern University, 633 Clark St, Evanston, IL 60208, USA.ORCID 0000-0002-2682-5639
Christopher Gwydion ChalklinCardiff Transplant Unit, University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff CF14 4XW, UK.
Ioannis KarniadakisCardiff Transplant Unit, University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff CF14 4XW, UK.
Vyron AlexandrouUrology Department, General Hospital of Thessaloniki "G. Gennimata-Agios Dimitrios", Elenis Zografou 2, 54634 Thessaloniki, Greece.
Nikos TteralliDepartment of General Surgery, North Hampshire NHS Foundation Trust, Basingstoke RG24 9NA, UK.
Eliot Carrington-WindoDepartment of General Surgery, Grange University Hospital, Caerleon Road, Llanfrechfa, Cwmbran NP44 8YN, UK.
Andreas PapacharalampousDepartment of Surgery Larnaca General Hospital Pandoras, 6301 Larnaca, Cyprus.
Kyriakos PsarrasSecond Surgical Propedeutic Department, School of Medicine, Ippokrateio General Hospital, Aristotle University of Thessaloniki, Konstantinoupoleos 49, 54642 Thessaloniki, Greece.
Cardiff and Vale University Health Board · GBAristotle University of Thessaloniki · GRLarnaca College · CYLlanfrechfa Grange Hospital · GBNHS Lothian · GBNorthwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal malignancies are the third-most common malignancies worldwide, with a rising incidence. Surgery remains the treatment of choice and adequate lymph node dissection is required for accurate staging. The objective of this study is to assess the use of carbon nanoparticles in lymph node tracing and resection in cases of colorectal cancer. For that purpose, we conducted a systematic review and meta-analysis of studies included in Medline, Scopus, Embase, Cochrane Library, and Google Scholar databases. In the end, ten studies with a total number of 1418 patients were included in the final statistical analysis. The meta-analysis carried out showed that the use of carbon nanoparticles results in an increased number of lymph nodes harvested (WMD 6.15, 95% CI 4.14 to 8.16,

Indexed as

Colorectal NeoplasmsNanoparticlesCarbonHumansLymphatic MetastasisLymph NodesCarboncarbon nanoparticlescolorectal cancerlymph nodes

Identifiers

PMID37894972
PMCPMC10607187
OpenAlexW4387743603

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.