Evidence map›Paper›PMID 37895006›Full record

ArticleInternational journal of molecular sciences2023

Effects of Mitochondrial Transplantation on Transcriptomics in a Polymicrobial Sepsis Model.

Seongmin Kim, Ji Heon Noh, Min Ji Lee, Ye Jin Park, Bo Mi Kim, Yun-Seok Kim, Sangik Hwang, Chungoo Park, Kyuseok Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Seongmin KimSchool of Biological Science and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0009-0006-6047-6416
Ji Heon NohDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Republic of Korea.
Min Ji LeeDepartment of Emergency Medicine, CHA University School of Medicine, Seongnam 13497, Republic of Korea.
Ye Jin ParkDepartment of Emergency Medicine, CHA University School of Medicine, Seongnam 13497, Republic of Korea.
Bo Mi KimDepartment of Emergency Medicine, CHA University School of Medicine, Seongnam 13497, Republic of Korea.
Yun-Seok KimDepartment of Emergency Medicine, CHA University School of Medicine, Seongnam 13497, Republic of Korea.
Sangik HwangDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Republic of Korea.
Chungoo ParkSchool of Biological Science and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.
Kyuseok KimDepartment of Emergency Medicine, CHA University School of Medicine, Seongnam 13497, Republic of Korea.ORCID 0000-0002-7991-9428
CHA University · KRChonnam National University · KRChungnam National University · KR

Funding

National Research Foundation of Korea NRF- 2020R1A2C3004508
6 · The paper itself

Abstract

Previously, we demonstrated that mitochondrial transplantation has beneficial effects in a polymicrobial sepsis model. However, the mechanism has not been fully investigated. Mitochondria have their own genes, and genomic changes in sepsis are an important issue in terms of pathophysiology, biomarkers, and therapeutic targets. To investigate the changes in transcriptomic features after mitochondrial transplantation in a polymicrobial sepsis model, we used a rat model of fecal slurry polymicrobial sepsis. Total RNA from splenocytes of sham-operated (SHAM,

Indexed as

SepsisTranscriptomeAnimalsGene Expression ProfilingMitochondriaRatscytokinesimmunosuppressionratssepsis

Identifiers

PMID37895006
PMCPMC10607172
OpenAlexW4387743778

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.