Evidence map›Paper›PMID 37895377›Full record

ArticleLife (Basel, Switzerland)2023

The Ratio of Monocytes to HDL-Cholesterol Is Associated with Cardiovascular Risk and Insulin Resistance in Patients with Rheumatoid Arthritis.

Alejandro Romo-Cordero, Marta González-Sierra, Juan Carlos Quevedo-Abeledo, Adrián Quevedo-Rodríguez, Fuensanta Gómez-Bernal, Antonia de Vera-González, Raquel López-Mejías, Alejandro Jiménez-Sosa, Candelaria Martín-González, Miguel Ángel González-Gay and 1 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Nonlinear Association Between Monocyte-to-HDL Ratio and Mortality in COPD: Evidence from NHANES.International journal of chronic obstructive pulmonary disease · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alejandro Romo-CorderoDivision of Internal Medicine, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Marta González-SierraDivision of Hospitalization-at-Home, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Juan Carlos Quevedo-AbeledoDivision of Rheumatology, Hospital Universitario Dr. Negrín, 35010 Las Palmas de Gran Canaria, Spain.
Adrián Quevedo-RodríguezDivision of Rheumatology, Hospital Universitario Dr. Negrín, 35010 Las Palmas de Gran Canaria, Spain.ORCID 0000-0001-5313-5142
Fuensanta Gómez-BernalDivision of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.ORCID 0000-0002-8597-1943
Antonia de Vera-GonzálezDivision of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Raquel López-MejíasEpidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Instituto de Investigación Sanitaria Marqués de Valdecilla (IDIVAL), Hospital Universitario Marqués de Valdecilla, 39011 Santander, Spain.
Alejandro Jiménez-SosaResearch Unit, Hospital Universitario de Canarias, 38320 Tenerife, Spain.ORCID 0000-0001-8732-2616
Candelaria Martín-GonzálezDivision of Internal Medicine, Hospital Universitario de Canarias, 38320 Tenerife, Spain.ORCID 0000-0002-4702-1840
Miguel Ángel González-GayDepartment of Medicine and Psychiatry, Universidad de Cantabria, 39005 Santander, Spain.ORCID 0000-0002-7924-7406
Iván Ferraz-AmaroInternal Medicine Department, Universidad de La Laguna, 38200 Tenerife, Spain.ORCID 0000-0003-0197-5267

Funding

Instituto de Salud Carlos III PI20/00084
6 · The paper itself

Abstract

The monocytes to high-density lipoprotein (HDL)-cholesterol ratio (MHR) indicates inflammation based on the anti-inflammatory properties of HDL-cholesterol as well as the pro-inflammatory effect of monocytes. Several studies have investigated MHR in various disorders, specifically in cardiovascular diseases. Consequently, MHR has been significantly associated with cardiovascular and all-cause mortality in the general population, regardless of established risk factors. However, its role in the augmented risk of cardiovascular disease found in rheumatoid arthritis (RA) has not been studied to date. This is a cross-sectional study that encompassed 430 patients with RA and 208 controls matched by sex and age. Complete blood cell count and complete lipid profile were evaluated. Multivariable analysis was made to analyze the relationship between MHR and RA disease and features subclinical carotid atherosclerosis, and traditional CV factors including insulin resistance and beta cell function indices. MHR values did not differ between controls and patients after multivariable adjustment (12 ± 6 vs. 11 ± 6,

Indexed as

insulin resistancemonocyte to high-density lipoprotein cholesterolrheumatoid arthritisSCORE2

Identifiers

PMID37895377
PMCPMC10608697

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.