Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors at 1 institution in 1 country.
Ioana Mirela VasincuDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0002-0873-2789
Maria ApotrosoaeiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.
Florentina LupascuDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.
Andreea-Teodora IacobDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0003-2530-3801
Simona-Eliza GiuscaDepartment of Morphofunctional Sciences, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.
Irina-Draga CaruntuDepartment of Morphofunctional Sciences, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.
Narcisa-Laura MarangociCentre of Advanced Research in Bionanoconjugates and Biopolymers, "Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0002-6629-6460
Anca Roxana PetroviciCentre of Advanced Research in Bionanoconjugates and Biopolymers, "Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0003-1387-3647
Gabriela Dumitrita StanciuAdvanced Research and Development Center for Experimental Medicine (CEMEX) "Prof. Ostin C. Mungiu", "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0003-4440-9628
Bogdan-Ionel TambaAdvanced Research and Development Center for Experimental Medicine (CEMEX) "Prof. Ostin C. Mungiu", "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0001-9868-1999
Bianca-Stefania ProfireDepartment of Internal Medicine, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.
Alin-Viorel FocsaDepartment of Drug Industry and Pharmaceutical Biotechnology, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.
Mariana PintealaCentre of Advanced Research in Bionanoconjugates and Biopolymers, "Petru Poni" Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0002-4021-982X
Lenuta ProfireDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy from Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0002-7953-3023
Grigore T. Popa University of Medicine and Pharmacy · RO
Funding
Grigore T. Popa University of Medicine and Pharmacy 10308/29.06.2020Grigore T. Popa University of Medicine and Pharmacy 30341/28.12.2017Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PNIII-P4-ID-PCE-1523 (contract nr. 161/2021)Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P4-ID-PCE-2020-2687 (contract nr. 244/2021
6 · The paper itself
Abstract
Generally, NSAIDs are weakly soluble in water and contain both hydrophilic and hydrophobic groups. One of the most widely used NSAIDs is ibuprofen, which has a poor solubility and high permeability profile. By creating dynamic, non-covalent, water-soluble inclusion complexes, cyclodextrins (CDs) can increase the dissolution rate of low aqueous solubility drugs, operating as a drug delivery vehicle, additionally contributing significantly to the chemical stability of pharmaceuticals and to reducing drug-related irritability. In order to improve the pharmacological and pharmacokinetics profile of ibuprofen, new thiazolidin-4-one derivatives of ibuprofen (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Complexes of Ibuprofen Thiazolidin-4-One Derivatives with β-Cyclodextrin: Characterization and In Vivo Release Profile and Biological Evaluation. · full record | Socratic