Evidence map›Paper›PMID 37896841›Full record

ArticleViruses2023

African Swine Fever Vaccine Candidate ASFV-G-ΔI177L Produced in the Swine Macrophage-Derived Cell Line IPKM Remains Genetically Stable and Protective against Homologous Virulent Challenge.

Manuel V Borca, Ayushi Rai, Nallely Espinoza, Elizabeth Ramirez-Medina, Edward Spinard, Lauro Velazquez-Salinas, Alyssa Valladares, Ediane Silva, Leeanna Burton, Amanda Meyers and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Manuel V BorcaPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.
Ayushi RaiPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.
Nallely EspinozaPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.
Elizabeth Ramirez-MedinaPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.
Edward SpinardPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.ORCID 0000-0001-7268-6580
Lauro Velazquez-SalinasPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.
Alyssa ValladaresPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.
Ediane SilvaNational Bio and Agro-Defense Facility, Agricultural Research Service, U.S. Department of Agriculture, Manhattan, KS 66502, USA.ORCID 0000-0001-5155-1361
Leeanna BurtonNational Bio and Agro-Defense Facility, Agricultural Research Service, U.S. Department of Agriculture, Manhattan, KS 66502, USA.
Amanda MeyersPlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.
Cyril G GayAgricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA.
Douglas P GladuePlum Island Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Orient, NY 11957, USA.ORCID 0000-0002-7894-0233
Agricultural Research Service · USOak Ridge Associated Universities · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ASFV vaccine candidate ASFV-G-ΔI177L has been shown to be highly efficacious in inducing protection against challenges with the parental virus, the Georgia 2010 isolate, as well as against field strains isolated from Vietnam. ASFV-G-ΔI177L has been shown to produce protection even when used at low doses (10

Indexed as

African Swine FeverAfrican Swine Fever VirusViral VaccinesAnimalsCell LineMacrophagesSus scrofaSwineViral ProteinsViral ProteinsViral VaccinesASFASFVASFV-G-ΔI177LASFV vaccine

Identifiers

PMID37896841
PMCPMC10612016
OpenAlexW4387457258

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.