Evidence map›Paper›PMID 37899209›Full record

ArticleEnvironmental health and preventive medicine2023

Life satisfaction and the risk of atherosclerotic cardiovascular disease in the general Japanese population: the Suita Study.

Ahmed Arafa, Rena Kashima, Yoshihiro Kokubo

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Article in Environmental health and preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ahmed ArafaDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.ORCID http://orcid.org/0000-0002-3335-2243
Rena KashimaDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Yoshihiro KokuboDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.ORCID http://orcid.org/0000-0002-0705-9449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtherosclerotic cardiovascular disease (ASCVD) is a major cause of morbidity and mortality. Life satisfaction is a measure of mental health with a potential cardioprotective role. This study aimed to investigate the association between life satisfaction and ASCVD risk in the general Japanese population.

methodWe used data from 6,877 people (30-84 years) registered in the Suita Study, a Japanese population-based prospective cohort study. All participants were free from stroke and coronary heart disease (CHD) at baseline. Then, participants were followed up for incident ASCVD, including cerebral infarction and CHD. Cox proportional hazards models were used to calculate the hazard ratio (HR) and 95% confidence interval (95% CI) of incident ASCVD according to life satisfaction.

resultsWithin 102,545 person-years (median follow-up = 16.6 years), 482 incident ASCVD events were identified. In the age- and sex-adjusted model, being very satisfied, rather satisfied, or not sure, compared to being dissatisfied with life, showed a lower risk of ASCVD: HR (95% CI) = 0.55 (0.41, 0.74), 0.67 (0.50, 0.89), and 0.57 (0.36, 0.88), respectively (p-trend < 0.001). The associations remained consistent after adjusting for stress and unfortunate events: HR (95% CI) = 0.57 (0.42, 0.77), 0.68 (0.50, 0.91), and 0.54 (0.35, 0.84), respectively (p-trend < 0.001). The results did not vary between cerebral infarction and CHD: HR (95% CI) for being very satisfied with life = 0.58 (0.37, 0.91) and 0.55 (0.36, 0.84), respectively.

conclusionLife satisfaction was inversely associated with the risk of ASCVD in the investigated general Japanese population.

Indexed as

AtherosclerosisCardiovascular DiseasesCoronary DiseaseAdultAgedAged, 80 and overCerebral InfarctionEast Asian PeopleHeart Disease Risk FactorsHumansMiddle AgedPersonal SatisfactionProspective StudiesRisk AssessmentRisk FactorsAtherosclerotic cardiovascular diseasesJapanLife satisfactionProspective cohort studies

Identifiers

PMID37899209
PMCPMC10613556

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.