Evidence map›Paper›PMID 37900943›Full record

ArticleFrontiers in molecular neuroscience2023

Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75

Raquel Comaposada-Baró, Andrea Benito-Martínez, Juan Julian Escribano-Saiz, María Luisa Franco, Lorenzo Ceccarelli, Isabel Calatayud-Baselga, Helena Mira, Marçal Vilar

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Raquel Comaposada-BaróMolecular Basis of Neurodegeneration Unit of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
Andrea Benito-MartínezMolecular Basis of Neurodegeneration Unit of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
Juan Julian Escribano-SaizMolecular Basis of Neurodegeneration Unit of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
María Luisa FrancoMolecular Basis of Neurodegeneration Unit of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
Lorenzo CeccarelliMolecular Basis of Neurodegeneration Unit of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
Isabel Calatayud-BaselgaStem Cells and Aging Units of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
Helena MiraStem Cells and Aging Units of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
Marçal VilarMolecular Basis of Neurodegeneration Unit of the Instituto de Biomedicina de Valencia CSIC, Valencia, Spain.
Instituto de Biomedicina de Valencia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degeneration of basal forebrain cholinergic neurons (BFCNs) is a hallmark of Alzheimer's disease (AD). However, few mouse models of AD recapitulate the neurodegeneration of the cholinergic system. The p75 neurotrophin receptor, p75

Indexed as

agingcholesterolcholinergic neurodegenerationNGF (nerve growth factor)p75 neurotrophin receptorTrkA (tropomyosin receptor kinase)

Identifiers

PMID37900943
PMCPMC10611523
OpenAlexW4387639324

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.