Evidence map›Paper›PMID 37903280›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

A mechano- and heat-gated two-pore domain K

Romane Idoux, Chloé Exbrayat-Héritier, Frédéric Sohm, Francisco Jaque-Fernandez, Elisabeth Vaganay, Christine Berthier, Sandrine Bretaud, Vincent Jacquemond, Florence Ruggiero, Bruno Allard

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Evolution of two-pore domain potassium channels and their gene expression in zebrafish embryos.Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Romane IdouxPhysiopathologie et Génétique du Neurone et du Muscle, Université Claude Bernard Lyon 1, CNRS UMR 5261, INSERM U1315, Faculté de Médecine Rockefeller, Lyon 69008, France.
Chloé Exbrayat-HéritierInstitut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, CNRS UMR 5242, Université Claude Bernard Lyon 1, Lyon 69007, France.
Frédéric SohmInstitut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, CNRS UMR 5242, Université Claude Bernard Lyon 1, Lyon 69007, France.
Francisco Jaque-FernandezPhysiopathologie et Génétique du Neurone et du Muscle, Université Claude Bernard Lyon 1, CNRS UMR 5261, INSERM U1315, Faculté de Médecine Rockefeller, Lyon 69008, France.ORCID 0000-0001-8260-8850
Elisabeth VaganayInstitut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, CNRS UMR 5242, Université Claude Bernard Lyon 1, Lyon 69007, France.
Christine BerthierPhysiopathologie et Génétique du Neurone et du Muscle, Université Claude Bernard Lyon 1, CNRS UMR 5261, INSERM U1315, Faculté de Médecine Rockefeller, Lyon 69008, France.
Sandrine BretaudInstitut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, CNRS UMR 5242, Université Claude Bernard Lyon 1, Lyon 69007, France.
Vincent JacquemondPhysiopathologie et Génétique du Neurone et du Muscle, Université Claude Bernard Lyon 1, CNRS UMR 5261, INSERM U1315, Faculté de Médecine Rockefeller, Lyon 69008, France.ORCID 0000-0003-4944-270X
Florence RuggieroInstitut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, CNRS UMR 5242, Université Claude Bernard Lyon 1, Lyon 69007, France.ORCID 0000-0003-2915-5359
Bruno AllardPhysiopathologie et Génétique du Neurone et du Muscle, Université Claude Bernard Lyon 1, CNRS UMR 5261, INSERM U1315, Faculté de Médecine Rockefeller, Lyon 69008, France.
Université Claude Bernard Lyon 1 · FR

Funding

Agence Nationale de la Recherche (ANR) FishandCol6Association Francaise contre les Myopathies MyoNeurALP2Centre National de la Recherche Scientifique (CNRS) UMR 5261 and 5242École Normale Supérieure de Lyon (ENSL) IGFLInstitut National de la Santé et de la Recherche Médicale (Inserm) U1315Université Claude Bernard Lyon 1 (UCBL) Biosciences
6 · The paper itself

Abstract

TRAAK channels are mechano-gated two-pore-domain K

Indexed as

Hot TemperatureZebrafishAnimalsChlorocebus aethiopsCOS CellsMiceMuscle Fibers, SkeletalMuscle, SkeletalK+ channelsingle-channel recordingskeletal muscle fibervoltage-clampzebrafish

Identifiers

PMID37903280
PMCPMC10636360
OpenAlexW4388017470

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.