Evidence map›Paper›PMID 37903947›Full record

ArticleScientific reports2023

The amphiregulin/EGFR axis has limited contribution in controlling autoimmune diabetes.

Arielle Raugh, Yi Jing, Matthew L Bettini, Maria Bettini

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Arielle RaughTranslational Biology and Molecular Medicine Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA.
Yi JingMicrobiology and Immunology Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA.
Matthew L BettiniDepartment of Pathology, University of Utah, Salt Lake City, UT, 84112, USA.
Maria BettiniDepartment of Pathology, University of Utah, Salt Lake City, UT, 84112, USA. maria.bettini@path.utah.edu.
Baylor College of Medicine · USUniversity of Utah · US

Funding

Training Program in Translational Biology and Molecular MedicineT32GM088129 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI ROONEY, CLIONA M., VAN DEN VEYVER, IGNATIA B · 2010 to 2019
$3.0M
Biophysical parameters of self-reactive TCR engagement in T1DR01AI172210 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Maria Bettini, Brian D Evavold · 2023 to 2026
$2.7M
Self-Reactive T Cell Development in Type 1 DiabetesR01DK114456 · NIDDK · UNIVERSITY OF UTAH · PI BETTINI, MATTHEW · 2018 to 2022
$1.9M
NIAID NIH HHS R01 AI172210NIDDK NIH HHS R01 DK114456NIGMS NIH HHS T32 GM088129
6 · The paper itself

Abstract

Conventional immunosuppressive functions of CD4

Indexed as

Diabetes Mellitus, Type 1Islets of LangerhansAmphiregulinAnimalsErbB ReceptorsMiceMice, Inbred NODT-Lymphocytes, RegulatoryAmphiregulinAreg protein, mouseEGFR protein, mouseErbB Receptors

Identifiers

PMID37903947
PMCPMC10616065
OpenAlexW4388015965

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.