Evidence map›Paper›PMID 37906092›Full record

ArticleeLife2023

Homeostatic control of deep sleep and molecular correlates of sleep pressure in

Budhaditya Chowdhury, Lakshman Abhilash, Antonio Ortega, Sha Liu, Orie Shafer

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

  1. [Correlations of calmodulin and neurotransmitters with polysomnographic parameters in patients with chronic insomnia disorder].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  2. Article
  3. Hypnotic Effects ofNutrients · 2026
    Article
  4. Article
  5. Inferring the genetic basis of sleep states inbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Current Evidence for Sleep States inCurrent sleep medicine reports · 2026
    Review
  8. The use ofFrontiers in cell and developmental biology · 2026
    Review
  9. Article
  10. 25 years ofFly · 2025
    Review
  11. Recognition of distinct sleep states inbioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Budhaditya Chowdhury *The Advanced Science Research Center, The City University of New York; The Graduate Center at the City University of New York, New York, United States.ORCID 0000-0003-3836-0426
Lakshman Abhilash *The Advanced Science Research Center, The City University of New York; The Graduate Center at the City University of New York, New York, United States.ORCID 0000-0002-9933-8989
Antonio OrtegaVIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.
Sha LiuVIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.
Orie ShaferThe Advanced Science Research Center, The City University of New York; The Graduate Center at the City University of New York, New York, United States.ORCID 0000-0001-7177-743X
The Graduate Center, CUNY · USVIB-KU Leuven Center for Brain & Disease Research · BE

Funding

Network Properties of Circadian Clock Modulation and EntrainmentR01NS077933 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ORIE T SHAFER · 2012 to 2026
$4.9M
Identification of Sleep Substances in the Brain Using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass SpectrometryR21NS131939 · NINDS · ADVANCED SCIENCE RESEARCH CENTER · PI SHAFER, ORIE T · 2023 to 2024
$432k
NINDS NIH HHS R01 NS077933NINDS NIH HHS R21 NS131939
6 · The paper itself

Abstract

Homeostatic control of sleep is typically addressed through mechanical stimulation-induced forced wakefulness and the measurement of subsequent increases in sleep. A major confound attends this approach: biological responses to deprivation may reflect a direct response to the mechanical insult rather than to the loss of sleep. Similar confounds accompany all forms of sleep deprivation and represent a major challenge to the field. Here, we describe a new paradigm for sleep deprivation in

Indexed as

Sleep DeprivationSleep, Slow-WaveAnimalsDrosophilaDrosophila melanogasterSleepWakefulnessdeprivationD. melanogasterEthoscopehomeostasisMALDI-TOF MSneurosciencesleep

Identifiers

PMID37906092
PMCPMC10642965
OpenAlexW4388034004

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.