Evidence map›Paper›PMID 37907122›Full record

ArticleClinical immunology (Orlando, Fla.)2023

Th2 cell clonal expansion at diagnosis in human type 1 diabetes.

Aditi Narsale, Francisco Almanza, Theo Tran, Breanna Lam, David Seo, Alisa Vu, S Alice Long, Laura Cooney, Elisavet Serti, Joanna D Davies

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical immunology (Orlando, Fla.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Aditi NarsaleSan Diego Biomedical Research Institute, 3525 John Hopkins Court, San Diego, CA 92121, USA. Electronic address: anarsale@sdbri.org.
Francisco AlmanzaSan Diego Biomedical Research Institute, 3525 John Hopkins Court, San Diego, CA 92121, USA. Electronic address: falmanza@sdbri.org.
Theo TranSan Diego Biomedical Research Institute, 3525 John Hopkins Court, San Diego, CA 92121, USA.
Breanna LamSan Diego Biomedical Research Institute, 3525 John Hopkins Court, San Diego, CA 92121, USA. Electronic address: bhlam@mit.edu.
David SeoSan Diego Biomedical Research Institute, 3525 John Hopkins Court, San Diego, CA 92121, USA.
Alisa VuSan Diego Biomedical Research Institute, 3525 John Hopkins Court, San Diego, CA 92121, USA. Electronic address: avu@sdbri.org.
S Alice LongBenaroya Research Institute, 1201 9(th) Ave, Seattle, WA 98101, USA. Electronic address: along@benaroyaresearch.org.
Laura CooneyImmune Tolerance Network, Ann Arbor, MI, USA. Electronic address: lcooney@immunetolerance.org.
Elisavet SertiImmune Tolerance Network, Bethesda, MD, USA. Electronic address: ESertiChrisos@hivresearch.org.
Joanna D DaviesSan Diego Biomedical Research Institute, 3525 John Hopkins Court, San Diego, CA 92121, USA. Electronic address: jdavies@sdbri.org.
San Diego Biomedical Research Institute · USImmune Tolerance Network · US

Funding

Immune Tolerance Network UM1 2023 SupplementUM1AI109565 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI Mark S Anderson, Jane Hoyt Buckner · 2014 to 2026
$451.6M
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600k
NIAID NIH HHS UM1 AI109565NIH HHS S10 OD026929
6 · The paper itself

Abstract

Soon after diagnosis with type 1 diabetes (T1D), many patients experience a period of partial remission. A longer partial remission is associated with a better response to treatment, but the mechanism is not known. The frequency of CD4

Indexed as

Diabetes Mellitus, Type 1Th2 CellsHumansAutoimmunityT cellsTh1/Th2Transcriptome

Identifiers

PMID37907122
PMCPMC12337782
OpenAlexW4388011852

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.