Evidence map›Paper›PMID 37907775›Full record

ArticleDrug safety2023

Drug Utilisation Patterns of Alternatives to Ranitidine-Containing Medicines in Patients Treated with Ranitidine: A Network Analysis of Data from Six European National Databases.

Johnmary T Arinze, Maria A J de Ridder, Dina Vojinovic, Hanne van Ballegooijen, Emanuil Markov, Talita Duarte-Salles, Peter Rijnbeek, Katia M C Verhamme

Open access · hybridAbstract read
In one paragraph

Article in Drug safety, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Utilization of Acid Suppressants After Withdrawal of Ranitidine in Korea: An Interrupted Time Series Analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Johnmary T ArinzeDepartment of Medical Informatics, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.ORCID 0000-0002-4981-6823
Maria A J de RidderDepartment of Medical Informatics, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Dina VojinovicIQVIA Solutions B.V., Amsterdam, The Netherlands.
Hanne van BallegooijenIQVIA Solutions B.V., Amsterdam, The Netherlands.
Emanuil MarkovIQVIA, Sofia, Bulgaria.
Talita Duarte-SallesDepartment of Medical Informatics, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Peter RijnbeekDepartment of Medical Informatics, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Katia M C VerhammeDepartment of Medical Informatics, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. k.verhamme@erasmusmc.nl.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRanitidine, a histamine H

objectivesThe aim was to study drug utilisation patterns of ranitidine and report discernible trends in treatment discontinuation and switching to alternative medications.

methodsThis retrospective, population-based cohort study was conducted using primary care records from six European countries between 2017 and 2023. To explore drug utilisation patterns, we calculated (1) incident use of ranitidine, other H

resultsDuring the study period, 385,273 new ranitidine users were observed, with most users being female and aged 18-74 years. Ranitidine was the most commonly prescribed H

conclusionsRanitidine was commonly used prior to referral, but it was subsequently discontinued and replaced primarily with PPIs.

Indexed as

Histamine H2 AntagonistsRanitidineCohort StudiesDrug UtilizationFemaleHumansMaleProton Pump InhibitorsRetrospective StudiesHistamine H2 AntagonistsProton Pump InhibitorsRanitidine

Identifiers

PMID37907775
PMCPMC10684403
OpenAlexW4388048899

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.