Evidence map›Paper›PMID 37908348›Full record

ArticleFrontiers in immunology2023

A fine mapping of single nucleotide variants and haplotype analysis of

José do Espírito Santo Junior, Josué Lacerda de Souza, Lener Santos da Silva, Cilana Chagas da Silva, Tuanny Arruda do Nascimento, Mara Lúcia Gomes de Souza, Alyne Farias da Cunha, Jacqueline da Silva Batista, José Pereira de Moura Neto, Marcus Vinitius de Farias Guerra and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Human sand fly challenge elicits saliva-specific innate and TbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

José do Espírito Santo JuniorPrograma de Pós-Graduação em Imunologia Básica e Aplicada, Instituto de Ciências Biológicas, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil.
Josué Lacerda de SouzaFaculdade de Medicina Nilton Lins, Universidade Nilton Lins, Manaus, Brazil.
Lener Santos da SilvaFaculdade de Medicina Nilton Lins, Universidade Nilton Lins, Manaus, Brazil.
Cilana Chagas da SilvaFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Brazil.
Tuanny Arruda do NascimentoFaculdade de Medicina Nilton Lins, Universidade Nilton Lins, Manaus, Brazil.
Mara Lúcia Gomes de SouzaFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Brazil.
Alyne Farias da CunhaInstituto Nacional de Pesquisa da Amazônia, Manaus, Brazil.
Jacqueline da Silva BatistaInstituto Nacional de Pesquisa da Amazônia, Manaus, Brazil.
José Pereira de Moura NetoFaculdade de Ciência Farmacêuticas, Universidade Federal do Amazonas, Manaus, Brazil.
Marcus Vinitius de Farias GuerraFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Brazil.
Rajendranath RamasawmyPrograma de Pós-Graduação em Imunologia Básica e Aplicada, Instituto de Ciências Biológicas, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil.
Universidade do Estado do Amazonas · BRFundação de Medicina Tropical · BRNational Institute of Amazonian Research · BRUniversidade Federal do Amazonas · BRUniversidade Nilton Lins · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Leishmaniasis continues to pose a substantial health burden in 97 countries worldwide. The progression and outcome of Methods: We investigated nine SNVs (SNV1rs1881457A>C, SNV2rs1295687C>G, SNV3rs2069744C>T, SNV4rs2069747C>T, SNV5rs20541A>G, SNV6rs1295685A>G, SNV7rs848A>C, SNV8rs2069750G >C, and SNV9rs847T>C) spanning the entire Results: Our analysis did not reveal any significant association between the SNVs and susceptibility/protection against Conclusions: Overall, our study identifies three haplotypes of

Indexed as

Leishmania guyanensisLeishmaniasis, CutaneousAnimalsCytokinesGenetic Predisposition to DiseaseHaplotypesHumansInterleukin-13Interleukin-4Interleukin-5MiceMice, Inbred C57BLNucleotidesPolymorphism, Single NucleotideCytokinesIL13 protein, humanIL4 protein, humanIL5 protein, humanInterleukin-13Interleukin-4Interleukin-5Nucleotidescutaneous leishmaniasisIL-13Leishmania guyanensissingle nucleotide variantssusceptibility

Identifiers

PMID37908348
PMCPMC10613733
OpenAlexW4387670241

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.