Evidence map›Paper›PMID 37915498›Full record

ArticleToxicology research2023

Involvement of functional senescence in efavirenz-induced toxicity in fruit fly.

Walter Mdekera Iorjiim, Simeon Omale, Samuel Ede, Chinelo Vera Ugokwe, Taiwo Emmanuel Alemika

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Kaempferol fromToxicology reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Walter Mdekera IorjiimDepartment of Pharmacology and Toxicology, University of Jos, Bauchi Road, Jos North, Postcode-930003, Plateau State, Nigeria.
Simeon OmaleDepartment of Pharmacology and Toxicology, University of Jos, Bauchi Road, Jos North, Postcode-930003, Plateau State, Nigeria.
Samuel EdeDepartment of Pharmacology and Toxicology, University of Jos, Bauchi Road, Jos North, Postcode-930003, Plateau State, Nigeria.
Chinelo Vera UgokweDepartment of Biochemistry, University of Jos, Bauchi Road, Jos North, Postcode-93003, Plateau State, Nigeria.
Taiwo Emmanuel AlemikaAfrica Centre of Excellence in Phytomedicine Research and Development (ACEPRD), University of Jos, Bauchi Road, Jos North, Postcode-930003 Plateau State, Nigeria.
University of Jos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We aimed in this article to assess the likeliness of efavirenz to induce functional senescence in Methods: Ten different concentrations of EFV were mixed with fly food and fed to 3-day-old flies orally for a 7 day LC Results: The calculated LC Conclusion: EFV exhibited ecotoxic potentials evidenced by age-related deficits in the fly's functional integrity such as sluggish movement, procreative deficiency, increased mortality, and oxidant-antioxidant inequality. Results from

Indexed as

acetylcholinesteraseDrosophila melanogasterefavirenzfunctional senescenceglutathione-S-transferaseoxidative stress

Identifiers

PMID37915498
PMCPMC10615817
OpenAlexW4386590473

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.