Evidence map›Paper›PMID 37917913›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Blood-based Transcriptomic and Proteomic Biomarkers of Emphysema.

Rahul Suryadevara, Andrew Gregory, Robin Lu, Zhonghui Xu, Aria Masoomi, Sharon M Lutz, Seth Berman, Jeong H Yun, Aabida Saferali, Min Hyung Ryu and 10 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 16 citations in OpenAlex.

  1. Observational
  2. A trans-omics gene-smoking interaction study of lung cancer based on consortium data.American journal of respiratory and critical care medicine · 2026
    Article
  3. Article
  4. Multi-omics to study chronic respiratory diseases and viral infections.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Radiomics for the Prediction of Emphysema Progression.Annals of the American Thoracic Society · 2025
    Article
  12. Lung Transcriptomics Link Emphysema to Barrier Dysfunction and Macrophage Subpopulations.American journal of respiratory and critical care medicine · 2025
    Article
  13. Pathophysiology and genomics of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  14. Multi Omics Applications in Biological Systems.Current issues in molecular biology · 2024
    Review
  15. Article
  16. Blood Biomarkers of Emphysema: What Can They Really Tell Us?American journal of respiratory and critical care medicine · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 2 countries.

Rahul SuryadevaraChanning Division of Network Medicine.ORCID 0000-0002-3182-0250
Andrew GregoryChanning Division of Network Medicine.
Robin LuChanning Division of Network Medicine.
Zhonghui XuChanning Division of Network Medicine.
Aria MasoomiDepartment of Electrical and Computer Engineering, Northeastern University, Boston, Massachusetts.
Sharon M LutzDepartment of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Seth BermanChanning Division of Network Medicine.
Jeong H YunChanning Division of Network Medicine.ORCID 0000-0002-4361-8295
Aabida SaferaliChanning Division of Network Medicine.
Min Hyung RyuChanning Division of Network Medicine.ORCID 0000-0003-3071-7363
Matthew MollChanning Division of Network Medicine.
Don D SinCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Craig P HershChanning Division of Network Medicine.ORCID 0000-0002-1342-4334
Edwin K SilvermanChanning Division of Network Medicine.
Jennifer DyDepartment of Electrical and Computer Engineering, Northeastern University, Boston, Massachusetts.
Katherine A PratteDepartment of Biostatistics and.
Russell P BowlerDivision of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado.ORCID 0000-0003-4651-363X
Peter J CastaldiChanning Division of Network Medicine.
Adel BoueizChanning Division of Network Medicine.ORCID 0000-0003-1638-8575
COPDGene investigators
Pulmonary and Critical Care Associates · USNortheastern University · USBrigham and Women's Hospital · USHarvard Pilgrim Health Care · USNational Jewish Health · USUniversity of British Columbia · CAVA Boston Healthcare System · US

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
COPD Susceptibility, Heterogeneity, and Progression: Proteomics and GeneticsR01HL133135 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MORITZ, ROBERT L, SILVERMAN, EDWIN K · 2017 to 2025
$7.2M
Using Integrative Genomics To Identify and Characterize Emphysema-Associated eQTLR01HL124233 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2014 to 2024
$7.1M
Imaging and multi-omics analyses to identify molecular subtypes of distinct emphysema patternsR01HL167072 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Adel El Boueiz · 2023 to 2026
$3.4M
Prospective Health Outcomes and Inflammatory Biomarkers Associated with e-Cigarette UseR01HL147326 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2019 to 2021
$1.5M
Integrative 'Omics of Transcriptome Complexity in COPDK01HL157613 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAFERALI, AABIDA · 2021 to 2025
$944k
Multi-omic Subtyping of Chronic Obstructive Pulmonary DiseaseK08HL136928 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HOBBS, BRIAN DANIEL · 2017 to 2021
$864k
Clinical significance and genetic determinants of novel imaging measures of emphysema distribution in 9,743 smokersK08HL141601 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI EL BOUEIZ, ADEL · 2018 to 2022
$853k
The role of COPD genetic risk factor HHIP on lymphocytic inflammationK08HL146972 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI YUN, JEONG H · 2020 to 2024
$848k
NHLBI NIH HHS K01 HL157613NHLBI NIH HHS K08 HL136928NHLBI NIH HHS K08 HL141601NHLBI NIH HHS K08 HL146972NHLBI NIH HHS P01 HL114501NHLBI NIH HHS R01 HL124233NHLBI NIH HHS R01 HL133135NHLBI NIH HHS R01 HL147326NHLBI NIH HHS R01 HL167072NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EmphysemaPulmonary Disease, Chronic ObstructivePulmonary EmphysemaBiomarkersGene Expression ProfilingHumansProteomicsTranscriptomeBiomarkersbiomarkersemphysemapredictionproteomicstranscriptomics

Identifiers

PMID37917913
PMCPMC10840768
OpenAlexW4388211905

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.