Evidence map›Paper›PMID 37918845›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Imaging Inflammation Past, Present, and Future: Focus on Cardioimmunology.

James T Thackeray, Kory J Lavine, Yongjian Liu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Frontiers in microbiology · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. CD45-targeted PET enables the visualization of inflammatory conditions.American journal of nuclear medicine and molecular imaging · 2025
    Article
  14. Viability assessment in an evolving field of heart failure treatment: still needed?The international journal of cardiovascular imaging · 2024
    Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

James T ThackerayDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; thackeray.james@mh-hannover.de.
Kory J LavineDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri; and.
Yongjian LiuDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · USMedizinische Hochschule Hannover · DE

Funding

Training/DisseminationP41EB025815 · NIBIB · WASHINGTON UNIVERSITY · PI Robert J. Gropler · 2018 to 2026
$12.7M
Specification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureR35HL161185 · NHLBI · WASHINGTON UNIVERSITY · PI Kory J. Lavine · 2022 to 2026
$4.3M
NHLBI NIH HHS R35 HL161185NIBIB NIH HHS P41 EB025815
6 · The paper itself

Abstract

Growing evidence implicates the immune system as a critical mediator of cardiovascular disease progression and a viable therapeutic target. Increased inflammatory cell activity is seen in the full spectrum of disorders from early-stage atherosclerosis through myocardial infarction, cardiomyopathy, and chronic heart failure. Although therapeutic strategies to modulate inflammation have shown promise in preclinical animal models, efficacy in patients has been modest owing in part to the variable severity of inflammation across individuals. The diverse leukocyte subpopulations involved in different aspects of heart disease pose a challenge to effective therapy, wherein adverse and beneficial aspects of inflammation require appropriate balance. Noninvasive molecular imaging enables tissue-level interrogation of inflammatory cells in the heart and vasculature to provide mechanistic and temporal insights into disease progression. Although clinical imaging has relied on

Indexed as

Fluorodeoxyglucose F18Myocardial InfarctionAnimalsHeartHumansInflammationMolecular ImagingFluorodeoxyglucose F18atherosclerosisleukocytemacrophagemolecular imagingmyocardial infarctionPET/CT

Identifiers

PMID37918845
PMCPMC12530639
OpenAlexW4388211862

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.