Evidence map›Paper›PMID 37927680›Full record

ArticleCureus2023

Prevalence of Side Effects of the AstraZeneca COVID-19 Vaccine: A Multicenter Experience From Pakistan.

Taimur Haider, Javeria Ali, Syed Mushhood Ali, Aqsa Syed Iftikhar, Ahsan Ali Siddiqui, Adeeba Salahuddin Khan, Javeria Ahmed Qamar, Khadija Sohail, Adnan Anwar, Atif A Hashmi

Abstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Taimur HaiderPaediatrics, District Headquarter Hospital, Jhang, PAK.
Javeria AliInternal Medicine, Abbasi Shaheed Hospital, Karachi, PAK.
Syed Mushhood AliInternal Medicine, Abbasi Shaheed Hospital, Karachi, PAK.
Aqsa Syed IftikharInternal Medicine, Liaquat National Hospital and Medical College, Karachi, PAK.
Ahsan Ali SiddiquiFamily Medicine, Tumair General Hospital, Riyadh, SAU.
Adeeba Salahuddin KhanEmergency Medicine, Ziauddin University, Karachi, PAK.
Javeria Ahmed QamarInternal Medicine, Dow University of Health Sciences, Karachi, PAK.
Khadija SohailInternal Medicine, Jinnah Sindh Medical University, Karachi, PAK.
Adnan AnwarPhysiology, Hamdard College of Medicine and Dentistry, Karachi, PAK.
Atif A HashmiPathology, Liaquat National Hospital and Medical College, Karachi, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The most efficient method of combating the coronavirus disease 2019 (COVID-19) pandemic would be to use effective, safe, and proven vaccines; however, their widespread use has been hampered partly by concerns over possible adverse effects. Therefore, this study aimed to assess the prevalence of Oxford/AstraZeneca vaccine side effects among participants. Methods This was a multicenter, cross-sectional study conducted using a non-probability sampling technique. The duration of the study was nine months, from February 1, 2022, to October 31, 2022. The study included 900 participants who provided informed consent and had received two doses of the AstraZeneca vaccine. Demographic characteristics of participants, such as gender, age, comorbidities, AstraZeneca vaccine with both doses along with booster dose, previous exposure to COVID-19 infection, and the prevalence of any local and systemic side effects following the first and second doses of vaccine, were documented. Results The study findings showed that of the 900 participants, 414 (46.0%) were males and 486 (54.0%) were females; their mean age was 40.72 ± 13.47 years. Among them, 198 (22.0%) had hypertension and 144 (16.0%) had diabetes mellitus. Following the first dose of the AstraZeneca vaccine, pain at the injection site was the most commonly reported side effect in 594 (66.0%) participants. Moreover, swelling at the injection site was the most commonly reported side effect in 522 (58.0%) participants after receiving the second dose of the vaccine. The level of satisfaction showed that the majority of the 648 participants (72.0%) were satisfied with their vaccination. Conclusion This study concluded that pain at the injection site was the most commonly reported side effect, followed by swelling and fever after the first dose of the vaccine. Following the second dose of the vaccine, adverse effects included headache, swelling, and burning at the injection site.

Indexed as

adverse effectsastrazenecacovid-19 vaccinepainside effects

Identifiers

PMID37927680
PMCPMC10625479

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.