Evidence map›Paper›PMID 37928749›Full record

ReviewScientifica2023

Nanoemulsion: An Emerging Novel Technology for Improving the Bioavailability of Drugs.

Preeti, Sharda Sambhakar, Rohit Malik, Saurabh Bhatia, Ahmed Al Harrasi, Chanchal Rani, Renu Saharan, Suresh Kumar, Geeta, Renu Sehrawat

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Scientifica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

PreetiBanasthali Vidyapith, Vanasthali Road, Aliyabad, Rajasthan 304022, India.ORCID https://orcid.org/0000-0001-7654-9719
Sharda SambhakarBanasthali Vidyapith, Vanasthali Road, Aliyabad, Rajasthan 304022, India.
Rohit MalikGurugram Global College of Pharmacy, Haily Mandi Rd, Farukh Nagar, Haryana 122506, India.ORCID https://orcid.org/0000-0003-2478-2556
Saurabh BhatiaSchool of Health Sciences, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India.ORCID https://orcid.org/0000-0002-8266-6927
Ahmed Al HarrasiNatural & Medical Sciences Research Centre, University of Nizwa, Birkat Al Mauz, Oman.ORCID https://orcid.org/0000-0002-0815-5942
Chanchal RaniGurugram Global College of Pharmacy, Haily Mandi Rd, Farukh Nagar, Haryana 122506, India.
Renu SaharanBanasthali Vidyapith, Vanasthali Road, Aliyabad, Rajasthan 304022, India.
Suresh KumarGanpati Institute of Pharmacy, Yamunanagar, Haryana 135102, India.
GeetaBanasthali Vidyapith, Vanasthali Road, Aliyabad, Rajasthan 304022, India.
Renu SehrawatSchool of Medical & Allied Sciences, K R Mangalam University, Gurugram, Haryana 122103, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmaceutical sector has made considerable strides recently, emphasizing improving drug delivery methods to increase the bioavailability of various drugs. When used as a medication delivery method, nanoemulsions have multiple benefits. Their small droplet size, which is generally between 20 and 200 nanometers, creates a significant interfacial area for drug dissolution, improving the solubility and bioavailability of drugs that are weakly water-soluble. Additionally, nanoemulsions are a flexible platform for drug administration across various therapeutic areas since they can encapsulate hydrophilic and hydrophobic medicines. Nanoemulsion can be formulated in multiple dosage forms, for example, gels, creams, foams, aerosols, and sprays by using low-cost standard operative processes and also be taken orally, topically, topically, intravenously, intrapulmonary, intranasally, and intraocularly. The article explores nanoemulsion formulation and production methods, emphasizing the role of surfactants and cosurfactants in creating stable formulations. In order to customize nanoemulsions to particular medication delivery requirements, the choice of components and production techniques is crucial in assuring the stability and efficacy of the finished product. Nanoemulsions are a cutting-edge technology with a lot of potential for improving medication bioavailability in a variety of therapeutic contexts. They are a useful tool in the creation of innovative pharmaceutical formulations due to their capacity to enhance drug solubility, stability, and delivery. Nanoemulsions are positioned to play a crucial role in boosting medication delivery and enhancing patient outcomes as this field of study continues to advance.

Identifiers

PMID37928749
PMCPMC10625491

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.