Evidence map›Paper›PMID 37928756›Full record

ArticleFrontiers in cardiovascular medicine2023

Analysis of immortal-time effect in post-infarction ventricular septal defect.

Héctor González-Pacheco, Jorge Arturo Ortega-Hernandez, Jesús Ángel Meza-López, Luis Alejandro Soliz-Uriona, Daniel Manzur-Sandoval, Rodrigo Gopar-Nieto, Diego Araiza-Garaygordobil, Daniel Sierra-Lara, Eduardo Arias-Sánchez, Juan Pablo Sandoval and 9 more

Abstract read
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In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Héctor González-Pacheco *Coronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Jorge Arturo Ortega-Hernandez *Coronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Jesús Ángel Meza-LópezCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Luis Alejandro Soliz-UrionaCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Daniel Manzur-SandovalCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Rodrigo Gopar-NietoCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Diego Araiza-GaraygordobilCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Daniel Sierra-LaraCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Eduardo Arias-SánchezDepartment of Interventional Cardiology, National Institute of Cardiology, Mexico City, Mexico.
Juan Pablo SandovalDepartment of Interventional Cardiology, National Institute of Cardiology, Mexico City, Mexico.
Alfredo Altamirano-CastilloCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Salvador Mendoza-GarcíaCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Arturo Arzate-RamírezCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Francisco Martin Baranda-TovarDepartment of Cardiovascular Critical Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Humberto MartinezDepartment of Cardiovascular Surgery, National Institute of Cardiology, Mexico City, Mexico.
Álvaro Montañez-OrozcoCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Luis Augusto Baeza-HerreraCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Alejandro Sierra-González De CossioCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.
Alexandra Arias-MendozaCoronary Care Unit, National Institute of Cardiology, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Time-fixed analyses have traditionally been utilized to examine outcomes in post-infarction ventricular septal defect (VSD). The aims of this study were to: (1) analyze the relationship between VSD closure/non-closure and mortality; (2) assess the presence of immortal-time bias. Material and methods: In this retrospective cohort study, patients with ST-elevation myocardial infarction (STEMI) complicated by VSD. Time-fixed and time-dependent Cox regression methodologies were employed. Results: The study included 80 patients: surgical closure ( Conclusions: This study highlights that using a fixed-time analytic approach in post-infarction VSD can result in immortal-time bias. Researchers should consider employing time-dependent methodologies.

Indexed as

acute myocardial infarctionconservative managementimmortal times biaspost-infarction ventricular septal defectST-elevation myocardial infarctionsurgical closuretranscatheter closure

Identifiers

PMID37928756
PMCPMC10620744

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.