Evidence map›Paper›PMID 37929021›Full record

ArticleFrontiers in endocrinology2023

Single nucleotide polymorphisms in vitamin D binding protein and 25-hydroxylase genes affect vitamin D levels in adolescents of Arab ethnicity in Kuwait.

Abdur Rahman, Mohamed Abu-Farha, Arshad Channanath, Maha M Hammad, Emil Anoop, Betty Chandy, Motasem Melhem, Fahd Al-Mulla, Thangavel Alphonse Thanaraj, Jehad Abubaker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Abdur RahmanDepartment of Food Science and Nutrition, College of Life Sciences, Kuwait University, Kuwait City, Kuwait.
Mohamed Abu-FarhaDepartment of Biochemistry & Molecular Biology, Dasman Diabetes Institute, Kuwait City, Kuwait.
Arshad ChannanathDepartment of Genetics & Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait.
Maha M HammadDepartment of Biochemistry & Molecular Biology, Dasman Diabetes Institute, Kuwait City, Kuwait.
Emil AnoopSpecial Services Facilities, Dasman Diabetes Institute, Kuwait City, Kuwait.
Betty ChandySpecial Services Facilities, Dasman Diabetes Institute, Kuwait City, Kuwait.
Motasem MelhemSpecial Services Facilities, Dasman Diabetes Institute, Kuwait City, Kuwait.
Fahd Al-MullaDepartment of Genetics & Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait.
Thangavel Alphonse ThanarajDepartment of Genetics & Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait.
Jehad AbubakerDepartment of Biochemistry & Molecular Biology, Dasman Diabetes Institute, Kuwait City, Kuwait.
Dasman Diabetes Institute · KWKuwait University · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D deficiency (VDD) is widespread in the Arab world despite ample sunshine throughout the year. In our previous study, lifestyle and socio-demographic factors could explain only 45% of variability in vitamin D levels in Kuwaiti adolescents, suggesting that genetics might contribute to VDD in this region. Single nucleotide polymorphisms (SNP) in the 25-hydroxylase (

Indexed as

Cholestanetriol 26-MonooxygenaseCytochrome P450 Family 2Vitamin DVitamin D-Binding ProteinVitamin D DeficiencyAdolescentArabsEthnicityHumansKuwaitMixed Function OxygenasesPolymorphism, Single NucleotideVitaminsCholestanetriol 26-MonooxygenaseCYP2R1 protein, humanCytochrome P450 Family 2Mixed Function OxygenasesVitamin DVitamin D-Binding ProteinVitaminsArab ethnicityCYP2R1GC globular genesingle nucleotide polymorphismvitamin D binding proteinvitamin D deficiency

Identifiers

PMID37929021
PMCPMC10623322
OpenAlexW4387821929

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.