Evidence map›Paper›PMID 37929030›Full record

ArticleFrontiers in endocrinology2023

Molecular interplay between ecdysone receptor and retinoid X receptor in regulating the molting of the Chinese mitten crab,

Xiaowen Chen, Xin Hou, Hao Yang, Hao Liu, Jun Wang, Chenghui Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The Role of Dietary Fatty Acids in Modulating Blue Crab (Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaowen ChenKey Laboratory of Freshwater Fisheries Germplasm Resources Certificated by The Ministry of Agriculture and Rural Affairs/National Demonstration Center for Experimental Fisheries Science Education/Shanghai Engineering/Research Center of Aquaculture, Shanghai Ocean University, Shanghai, China.
Xin HouKey Laboratory of Freshwater Fisheries Germplasm Resources Certificated by The Ministry of Agriculture and Rural Affairs/National Demonstration Center for Experimental Fisheries Science Education/Shanghai Engineering/Research Center of Aquaculture, Shanghai Ocean University, Shanghai, China.
Hao YangKey Laboratory of Freshwater Fisheries Germplasm Resources Certificated by The Ministry of Agriculture and Rural Affairs/National Demonstration Center for Experimental Fisheries Science Education/Shanghai Engineering/Research Center of Aquaculture, Shanghai Ocean University, Shanghai, China.
Hao LiuKey Laboratory of Freshwater Fisheries Germplasm Resources Certificated by The Ministry of Agriculture and Rural Affairs/National Demonstration Center for Experimental Fisheries Science Education/Shanghai Engineering/Research Center of Aquaculture, Shanghai Ocean University, Shanghai, China.
Jun WangKey Laboratory of Freshwater Fisheries Germplasm Resources Certificated by The Ministry of Agriculture and Rural Affairs/National Demonstration Center for Experimental Fisheries Science Education/Shanghai Engineering/Research Center of Aquaculture, Shanghai Ocean University, Shanghai, China.
Chenghui WangKey Laboratory of Freshwater Fisheries Germplasm Resources Certificated by The Ministry of Agriculture and Rural Affairs/National Demonstration Center for Experimental Fisheries Science Education/Shanghai Engineering/Research Center of Aquaculture, Shanghai Ocean University, Shanghai, China.
Ministry of Agriculture and Rural Affairs · CNShanghai Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Molting is a pivotal biological process regulated by the ecdysteroid signaling pathway that requires molecular coordination of two transcription factors, Ecdysone receptor (EcR) and ultraspiracle (USP) in arthropods. However, the molecular interplay of EcR and Retinoid X receptor (RXR), the crustacean homolog of USP in the ecdysteroid signaling pathway, is not well understood. Methods: In this study, we conducted temporal and spatial expression, co-immunoprecipitation (CO-IP), and luciferase reporter assay experiments to investigate the molecular function and interplay of EcR and RXR during the molting process of the Chinese mitten crab, Results: The results showed that the expression level of Conclusions: Our study unveiled the diverse molecular function and molecular interplay of EcR and RXR;

Indexed as

EcdysteroidsMoltingLuciferasesReceptors, SteroidRetinoid X Receptorsecdysone receptorEcdysteroidsLuciferasesReceptors, SteroidRetinoid X Receptorsecdysone receptorecdysteroid signaling pathwaymolecular interplaymoltingretinoid X receptor

Identifiers

PMID37929030
PMCPMC10621794
OpenAlexW4387776817

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.