Evidence map›Paper›PMID 37929964›Full record

ArticlemSphere2023

An expanded toolkit of drug resistance cassettes for

Justin B Gregor, Victor A Gutierrez-Schultz, Smriti Hoda, Kortany M Baker, Debasmita Saha, Madeline G Burghaze, Cynthia Vazquez, Kendra E Burgei, Scott D Briggs

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Micafungin exposure drives multidrug resistance inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. The multidrug-resistantCurrent research in microbial sciences · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Justin B GregorDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.ORCID 0000-0003-2634-3178
Victor A Gutierrez-SchultzDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Smriti HodaDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Kortany M BakerDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Debasmita SahaDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Madeline G BurghazeDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Cynthia VazquezDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Kendra E BurgeiDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Scott D BriggsDepartment of Biochemistry, Purdue University, West Lafayette, Indiana, USA.ORCID 0000-0003-2852-3594
Purdue University West Lafayette · US

Funding

SET Domain Epigenetic Factors Govern Antifungal Drug Efficacy and Fungal PathogenesisR01AI136995 · NIAID · PURDUE UNIVERSITY · PI BRIGGS, SCOTT D · 2018 to 2022
$1.9M
Drug Discovery in Infectious Disease TrainingT32AI148103 · NIAID · PURDUE UNIVERSITY · PI STAHELIN, ROBERT VIRGIL, YEO, YOON · 2020 to 2024
$949k
NIAID NIH HHS R01 AI136995NIAID NIH HHS T32 AI148103
6 · The paper itself

Abstract

importanceThe increasing problem of drug resistance and emerging pathogens is an urgent global health problem that necessitates the development and expansion of tools for studying fungal drug resistance and pathogenesis. Prior studies in

Indexed as

Candida albicansCandida glabrataAntifungal AgentsCandidaCandida aurisDrug Resistance, FungalErgosterolAntifungal AgentsErgosterolantifungal drug resistanceazole antifungal drugsCandida albicansCandida aurisCandida glabrataCRISPR-RNPERG5 and ERG3ergosterol pathwayKanMX and BleMXtoxic sterols

Identifiers

PMID37929964
PMCPMC10732037
OpenAlexW4388423244

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.