Evidence map›Paper›PMID 37933966›Full record

ArticleJournal of virology2023

Low-temperature immunization attenuates the residual virulence of

Ruoyun Zeng, Jiajie Fu, Weiqiang Pan, Zhipeng Zhan, Shaoping Weng, Changjun Guo, Jianguo He

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ruoyun Zeng *State Key Laboratory for Biocontrol / Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), School of Marine Sciences, Sun Yat-sen University , Guangzhou, Guangdong, China.ORCID 0009-0004-0164-0381
Jiajie Fu *State Key Laboratory for Biocontrol / Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), School of Marine Sciences, Sun Yat-sen University , Guangzhou, Guangdong, China.
Weiqiang PanState Key Laboratory for Biocontrol / Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), School of Marine Sciences, Sun Yat-sen University , Guangzhou, Guangdong, China.
Zhipeng ZhanState Key Laboratory for Biocontrol / Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), School of Marine Sciences, Sun Yat-sen University , Guangzhou, Guangdong, China.
Shaoping WengState Key Laboratory for Biocontrol / Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), School of Marine Sciences, Sun Yat-sen University , Guangzhou, Guangdong, China.
Changjun GuoState Key Laboratory for Biocontrol / Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), School of Marine Sciences, Sun Yat-sen University , Guangzhou, Guangdong, China.ORCID 0000-0003-3223-6176
Jianguo HeState Key Laboratory for Biocontrol / Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), School of Marine Sciences, Sun Yat-sen University , Guangzhou, Guangdong, China.
Sun Yat-sen University · CNSouth China Agricultural University · CN

Funding

Agriculture Research System of China (China's Agricultural Research System) CARS-46Basic and Appiled Basic Research Project of Guangzhou Science and Technology Plan Project 202102020299GDSTC | Basic and Applied Basic Research Foundation of Guangdong Province 2021A1515010647Guangdong Laboratory for Linnan modern agriculture NZ2021018Key Research and Development of Guangdong 2021B0202040002 and 2022B1111030001MOST | National Key Research and Development Program of China (NKPs) 2022YFE020517
6 · The paper itself

Abstract

importanceGlobal aquaculture production yielded a record of 122.9 million tons in 2022. However, ~10% of farmed aquatic animal production is lost each year due to various infectious diseases, resulting in substantial economic waste. Therefore, the development of vaccines is important for the prevention and control of aquatic infectious diseases. Gene-deletion live attenuated vaccines are efficacious because they mimic natural pathogen infection and generate a strong antibody response, thus showing good potential for administration via immersion. However, most gene-deletion viruses still have residual virulence, and thus, gene-deletion immersion vaccines for aquatic viruses are rarely developed. In this study, an

Indexed as

Fish DiseasesIridoviridaeViral VaccinesAnimalsCold TemperatureImmersionImmunizationVaccines, AttenuatedVirulenceVaccines, AttenuatedViral Vaccinesgene-deletion immersion vaccineimmersion vaccineISKNV

Identifiers

PMID37933966
PMCPMC10688326
OpenAlexW4388464439

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.