ArticleBrain and behavior2023
Predictive value of the systemic immune inflammation (SII) index for stroke-associated pneumonia.
Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Systemic Inflammation Mediates the Association Between Admission Hyperglycemia and Pulmonary Infection or Prognosis in Acute Ischemic Stroke.Mediators of inflammation · 2026Article
- Advanced radiomics techniques applied on carotid duplex ultrasound data predict adverse outcomes in acute ischemic stroke.Frontiers in neurology · 2026Article
- Systemic immune-inflammation index, stress hyperglycemia ratio and triglyceride-glucose index in acute ischemic stroke: an integrated inflammation-stress-metabolism perspective.Frontiers in neurology · 2026Review
- Inflammation-Based Hematologic Indices as Prognostic Markers in Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension: A Hypothesis-Generating Registry Study.International journal of molecular sciences · 2025Article
- Predictors of response to accelerated rTMS in the treatment of treatment-resistant depression.European archives of psychiatry and clinical neuroscience · 2025Article
- Construction and evaluation of a nomogram model for predicting the risk of hospital-acquired pneumonia in elderly patients with acute ischemic stroke.BMC geriatrics · 2025Article
- Early Predictive Value of the Glucose-to-Lymphocyte Ratio for the Occurrence of Stroke-Associated Pneumonia.Brain and behavior · 2025Article
- Comparison of the Predictive Value of Neutrophil Percentage-to-Albumin Ratio and Modified Glasgow Prognostic Score for the Risk of Stroke-Associated Pneumonia Among Stroke Patients.International journal of general medicine · 2025Article
- Systemic Immune Inflammation Index (SII) and Prognostic Nutritional Index (PNI) Associated with Prolonged Intensive Care Unit (ICU) Stay in Patients with Pneumonia Complicated with Respiratory Failure.International journal of general medicine · 2025Article
- Elevated systemic immune-inflammation index is associated with stroke-associated pneumonia in acute ischemic stroke: a retrospective cohort study.Frontiers in neurology · 2025Article
- A Role for Systemic Inflammation in Stroke-Associated Infection and the Long-Term Prognosis of Acute Ischemic Stroke: A Mediation Analysis.Journal of inflammation research · 2024Article
- Systemic immune inflammation index as a predictor of disease severity in tetanus patients: A retrospective observational study.PloS one · 2024Observational
- Predictive value of the systemic immune inflammation (SII) index for stroke-associated pneumonia.Brain and behavior · 2023Article
- Exosomal programmed death-ligand 1 is associated with post-intracerebral hemorrhage pneumonia.Brain circulationArticle
- Association between systemic immune-inflammation index and all-cause mortality in ischemic stroke patients.Frontiers in neurologyArticle
- Predictive value of water swallow test score, serum albumin, and systemic immune-inflammation index for stroke-associated pneumonia in patients with acute isolated pontine infarction.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the predictive value of the systemic immune inflammation (SII) index on the occurrence of stroke-associated pneumonia (SAP) in patients with acute stroke.
methodsData of patients with or without a previous history of pulmonary who visited the First Affiliated Hospital of Kunming Medical University within 24 h of the onset of stroke were collected between January 2017 and December 2019. Patient's demographic data, stroke type, past medical history, National Institutes of Health Stroke Scale score, Glasgow Coma score, and laboratory tests were collected. Logistic regression models and receiver-operating characteristic (ROC) curves were used to investigate the predictive value of SII for the development of SAP in patients with stroke.
resultsWe included 395 patients with acute stroke, with a mean age of 63.89 ± 13.42 years, of whom 340 (86.1%) had ischemic stroke, and 55 (13.9%) had hemorrhagic stroke. Out of 395, 113 (28.6%) had SAP and 282 (71.4%) did not, and the SII level in the SAP group was higher than that of the non-SAP group (p < .05). Logistic regression analysis of patients with stroke showed that higher SII was a risk factor for SAP in patients with stroke (per 100 units, HR = 1.081, 95% CI: 1.035-1.130, p < .001), and tertile grouping of SII showed that the risk of SAP was 5.059 times higher in the SIIQ3 group than in the SIIQ1 group (95% CI: 2.061-12.418, p < .001). ROC curve analysis indicated that the SII index had predictive value for the occurrence of SAP in patients with stroke, with an area under the curve of 0.752 (95% CI: 0.698-0.806). When the cutoff value was 861.01, the SII predicted SAP in patients with stroke with a sensitivity of 61.9% and a specificity of 76.2%.
conclusionHigher SII is an independent risk factor for the development of SAP in patients with stroke and has some predictive value for the development of SAP.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.