Trial reportPediatrics2023
Umbilical Cord Milking Versus Delayed Cord Clamping in Infants 28 to 32 Weeks: A Randomized Trial.
Trial report in Pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Singapore Neonatal Resuscitation Guidelines 2026.Singapore medical journal · 2026Guideline
- Hemodynamic effects of umbilical cord milking versus early cord clamping in nonvigorous intrauterine growth restricted neonates: a randomized controlled trial.European journal of pediatrics · 2026Trial
- Effect of delayed cord clamping and cord milking on cerebral oxygenation and cardiovascular function: a secondary analysis of the PCI trial.European journal of pediatrics · 2026Trial
- Deferred Cord Clamping With High Oxygen in Extremely Preterm Infants: A Randomized Clinical Trial.JAMA pediatrics · 2025Trial
- "Cut umbilical cord milking (C-UCM) in preterm twin gestational births-a randomized controlled trial".European journal of pediatrics · 2025Trial
- Resuscitation With Placental Circulation Intact Compared With Cord Milking: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Two-Year Outcomes of Umbilical Cord Milking in Nonvigorous Infants: A Secondary Analysis of the MINVI Randomized Clinical Trial.JAMA network open · 2024Trial
- A randomised controlled trial comparing umbilical cord milking to delayed cord clamping at birth in preterm infants 28-36 weeks gestational age.European journal of pediatrics · 2024Trial
- Care of the Newborn and Cord During the Third Stage of Labour (Scientific Impact Paper No. 78).BJOG : an international journal of obstetrics and gynaecology · 2026Review
- Impact of duration of delayed umbilical cord clamping on days of phototherapy in preterm neonates 23-35 weeks gestation-a retrospective, single-center cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Fetal Hemoglobin in Preterm Infants After Resuscitation with Immediate Cord Clamping, Delayed Cord Clamping, or Cord Milking.Children (Basel, Switzerland) · 2025Article
- Towards better enrollment decision-making for perinatal clinical research: Reconsidering recruitment and consent processes to support family values and preferences.Seminars in perinatology · 2025Review
- Impact of delayed cord clamping on respiratory distress in late preterm and early term infants in elective cesarean section: a single centre, phase Ⅲ, randomised controlled trial.EClinicalMedicine · 2025Article
- Cardiorespiratory interactions during the transitional period in extremely preterm infants: a narrative review.Pediatric research · 2025Review
- Review
- The performance of the practices associated with the occurrence of severe intraventricular hemorrhage in the very premature infants: data analysis from the Chinese neonatal network.BMC pediatrics · 2024Article
Corrections and comments
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Authors and funding
40 authors at 18 institutions in 4 countries.
Funding
Abstract
objectivesTo determine whether rate of severe intraventricular hemorrhage (IVH) or death among preterm infants receiving placental transfusion with UCM is noninferior to delayed cord clamping (DCC).
methodsNoninferiority randomized controlled trial comparing UCM versus DCC in preterm infants born 28 to 32 weeks recruited between June 2017 through September 2022 from 19 university and private medical centers in 4 countries. The primary outcome was Grade III/IV IVH or death evaluated at a 1% noninferiority margin.
resultsAmong 1019 infants (UCM n = 511 and DCC n = 508), all completed the trial from birth through initial hospitalization (mean gestational age 31 weeks, 44% female). For the primary outcome, 7 of 511 (1.4%) infants randomized to UCM developed severe IVH or died compared to 7 of 508 (1.4%) infants randomized to DCC (rate difference 0.01%, 95% confidence interval: (-1.4% to 1.4%), P = .99).
conclusionsIn this randomized controlled trial of UCM versus DCC among preterm infants born between 28 and 32 weeks' gestation, there was no difference in the rates of severe IVH or death. UCM may be a safe alternative to DCC in premature infants born at 28 to 32 weeks who require resuscitation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.