Evidence map›Paper›PMID 37942313›Full record

ArticleFrontiers in immunology2023

Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies.

Paul Noe, Joy H Wang, Kyu Chung, Zhiyong Cheng, Jessica J Field, Xiaomeng Shen, Christa L Cortesio, Cinthia V Pastuskovas, Hyewon Phee, Kristin V Tarbell and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Paul NoeOncology Research, Amgen Research, South San Francisco, CA, United States.
Joy H WangOncology Research, Amgen Research, South San Francisco, CA, United States.
Kyu ChungOncology Research, Amgen Research, South San Francisco, CA, United States.
Zhiyong ChengOncology Research, Amgen Research, South San Francisco, CA, United States.
Jessica J FieldPharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, CA, United States.
Xiaomeng ShenPharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, CA, United States.
Christa L CortesioTherapeutics Discovery, Amgen Research, South San Francisco, CA, United States.
Cinthia V PastuskovasPharmacokinetics and Drug Metabolism, Amgen Research, South San Francisco, CA, United States.
Hyewon PheeOncology Research, Amgen Research, South San Francisco, CA, United States.
Kristin V TarbellOncology Research, Amgen Research, South San Francisco, CA, United States.
Jackson G EgenOncology Research, Amgen Research, South San Francisco, CA, United States.
Amy-Jo CasbonOncology Research, Amgen Research, South San Francisco, CA, United States.
Amgen (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional type 1 dendritic cells (cDC1s) are superior in antigen cross-presentation and priming CD8

Indexed as

Interferon Type INeoplasmsAntigen PresentationCD8-Positive T-LymphocytesDendritic CellsHumansInterferon Type Iantibody IFN fusionconventional type I DCsdendritic cellsimmunogenicityimmunotherapyinterferonpharmacokinetics

Identifiers

PMID37942313
PMCPMC10628189
OpenAlexW4387899570

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.