Evidence map›Paper›PMID 37942336›Full record

ReviewFrontiers in immunology2023

Immunomodulatory properties of morphine and the hypothesised role of long-term opioid use in the immunopathogenesis of tuberculosis.

Vipula R Bataduwaarachchi, Smn Hansanie, Neesha Rockwood, Leon Gerard D'Cruz

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Vipula R BataduwaarachchiDepartment of Pharmacology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Smn HansanieDepartment of Pharmacology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Neesha RockwoodDepartment of Microbiology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Leon Gerard D'CruzResearch and Innovation Department, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom.
University of Colombo · LKPortsmouth Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological studies have shown high tuberculosis (TB) prevalence among chronic opioid users. Opioid receptors are found on multiple immune cells and immunomodulatory properties of opioids could be a contributory factor for ensuing immunosuppression and development or reactivation of TB. Toll-like receptors (TLR) mediate an immune response against microbial pathogens, including

Indexed as

Mycobacterium tuberculosisTuberculosisAnalgesics, OpioidHumansImmunityMorphineAnalgesics, OpioidMorphineimmunopathogenesis of tuberculosisimmunosuppressionmorphineopioid receptorsopioidstoll-like receptors

Identifiers

PMID37942336
PMCPMC10628761
OpenAlexW4388264301

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.