Evidence map›Paper›PMID 37942645›Full record

ReviewStroke2023

Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke.

Edgar A Samaniego, Johannes Boltze, Patrick D Lyden, Michael D Hill, Bruce C V Campbell, Gisele Sampaio Silva, Kevin N Sheth, Marc Fisher, Argye E Hillis, Thanh N Nguyen and 7 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. The Immunologic Underpinnings of Post-Stroke Depression.Biological psychiatry global open science · 2025
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 5 countries.

Edgar A SamaniegoDepartment of Neurology, Radiology and Neurosurgery, University of Iowa Carver College of Medicine (E.A.S.).ORCID 0000-0003-2764-2268
Johannes BoltzeSchool of Life Sciences, University of Warwick, Coventry, United Kingdom (J.B.).ORCID 0000-0003-3956-4164
Patrick D LydenZilkha Neurogenetic Institute of the Keck School of Medicine at USC, Los Angeles, CA (P.D.L.).ORCID 0000-0001-6170-4042
Michael D HillDepartment of Clinical Neuroscience and Hotchkiss Brain Institute, University of Calgary and Foothills Medical Centre, Canada (M.D.H.).ORCID 0000-0002-6269-1543
Bruce C V CampbellDepartment of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia (B.C.V.C.).ORCID 0000-0003-3632-9433
Gisele Sampaio SilvaDepartment of Neurology and Neurosurgery, Federal University of São Paulo, Brazil (G.S.S.).ORCID 0000-0002-3247-3123
Kevin N ShethDepartment of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven, CT (K.N.S.).
Marc FisherDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA (M.F.).ORCID 0000-0002-6116-475X
Argye E HillisDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD (A.E.H.).ORCID 0000-0002-5192-1171
Thanh N NguyenDepartment of Neurology, Boston Medical Center, MA (T.N.N.).ORCID 0000-0002-2810-1685
Davide CaroneOxford University Hospitals NHS Foundation Trust, United Kingdom (D.C.).
Christopher G FavillaDepartment of Neurology, University of Pennsylvania Philadelphia (C.G.F.).ORCID 0000-0003-0871-9549
Emir DeljkichImperative Care (E.D.).ORCID 0009-0009-4785-5683
Gregory W AlbersDepartments of Neurology (G.W.A., M.G.L.), Stanford University, CA.ORCID 0000-0003-0263-4632
Jeremy J HeitRadiology and Neurosurgery (J.J.H.), Stanford University, CA.ORCID 0000-0003-1055-8000
Maarten G LansbergDepartments of Neurology (G.W.A., M.G.L.), Stanford University, CA.ORCID 0000-0002-3545-6927
XIIth Stroke Treatment Academic Industry Roundtable
Stanford University · USTwitter (United States) · USBeth Israel Deaconess Medical Center · USBoston Medical Center · USFoothills Medical Centre · CAJohns Hopkins University · USKeck Hospital of USC · USOxford University Hospitals NHS Trust · GBSt. Christopher's Hospital for Children · USThe Royal Melbourne Hospital · AUUniversidade Federal de São Paulo · BRUniversity of Warwick · GBYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
CTP to predict Response to recanalization in Ischemic Stroke Project (CRISP)R01NS075209 · NINDS · STANFORD UNIVERSITY · PI LANSBERG, MAARTEN G · 2011 to 2023
$6.0M
NCATS NIH HHS UL1 TR001863NINDS NIH HHS R01 NS075209
6 · The paper itself

Abstract

STAIR XII (12th Stroke Treatment Academy Industry Roundtable) included a workshop to discuss the priorities for advancements in neuroimaging in the diagnostic workup of acute ischemic stroke. The workshop brought together representatives from academia, industry, and government. The participants identified 10 critical areas of priority for the advancement of acute stroke imaging. These include enhancing imaging capabilities at primary and comprehensive stroke centers, refining the analysis and characterization of clots, establishing imaging criteria that can predict the response to reperfusion, optimizing the Thrombolysis in Cerebral Infarction scale, predicting first-pass reperfusion outcomes, improving imaging techniques post-reperfusion therapy, detecting early ischemia on noncontrast computed tomography, enhancing cone beam computed tomography, advancing mobile stroke units, and leveraging high-resolution vessel wall imaging to gain deeper insights into pathology. Imaging in acute ischemic stroke treatment has advanced significantly, but important challenges remain that need to be addressed. A combined effort from academic investigators, industry, and regulators is needed to improve imaging technologies and, ultimately, patient outcomes.

Indexed as

Brain IschemiaIschemic StrokeStrokeHumansNeuroimagingThrombectomyThrombolytic TherapyTreatment Outcomecerebral infarctionischemic strokeneuroimagingreperfusionthrombectomy

Identifiers

PMID37942645
PMCPMC10841844
OpenAlexW4388539569

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.