Evidence map›Paper›PMID 37944089›Full record

ArticleJCO global oncology2023

Global Cancer Drug Development-A Report From the 2022 Accelerating Anticancer Agent Development and Validation Meeting.

Brooke E Wilson, Richard Sullivan, Richard Peto, Bello Abubakar, Christopher Booth, Gustavo Werutsky, Cary Adams, Agnes Saint-Raymond, Thomas R Fleming, Kim Lyerly and 1 more

Abstract read
In one paragraph

Article in JCO global oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. A Delphi Study to Identify Priority Indicators for Formulary Selection of Innovative Anticancer Drugs in China.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. A zebrafish colorectal xenograft model for chemotherapy response.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brooke E WilsonDivision of Cancer Care and Epidemiology, Queen's Cancer Research Institute, Kingston, Canada.ORCID 0000-0001-6557-7298
Richard SullivanInstitute of Cancer Policy, King's College London, London, United Kingdom.ORCID 0000-0002-6435-1825
Richard PetoDepartment of Medical Statistics and Epidemiology, University of Oxford, Oxford, United Kingdom.
Bello AbubakarDepartment of Radiotherapy and Oncology, National Hospital Abuja, Abuja, Nigeria.ORCID 0000-0002-6884-6761
Christopher BoothDivision of Cancer Care and Epidemiology, Queen's Cancer Research Institute, Kingston, Canada.ORCID 0000-0002-1353-3653
Gustavo WerutskyDepartment of Medical Oncology, Hospital São Lucas, Porto Alegre, Brazil.ORCID 0000-0001-6271-105X
Cary AdamsUnion for International Cancer Control, Geneva, Switzerland.
Agnes Saint-RaymondInternational Affairs Division, European Medicines Agency, Amsterdam, the Netherlands.ORCID 0000-0001-8056-8453
Thomas R FlemingDepartment of Statistics, University of Washington, Seattle, WA.
Kim LyerlyDepartments of Surgery, Pathology, and Immunology, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-0063-4770
Julie R GralowAmerican Society of Clinical Oncology, Alexandria, VA.ORCID 0000-0003-3837-9928

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapidly expanding systemic treatment options, combined with improved screening, diagnostic, surgical, and radiotherapy techniques, have led to improved survival outcomes for many cancers over time. However, these overall survival gains have disproportionately benefited patients in high-income countries, whereas patients in low- and middle-income countries (LMICs) continue to experience challenges in accessing timely and guideline concordant care. In September 2022, the Accelerating Anticancer Agent Development and Validation workshop was held, focusing on global cancer drug development. Panelists discussed key barriers such as the lack of diagnostic services and human resources, drug accessibility and affordability, lack of research infrastructure, and regulatory and authorization challenges, with a particular focus on Africa and Latin America. Potential opportunities to improve access and affordability were reviewed, such as the importance of prioritizing investments in diagnostics, investing health infrastructure and work force planning, coordinated drug procurement efforts and streamlined regulatory processing, incentivized pricing through regulatory change, and the importance of developing and promoting clinical trials that can answer relevant clinical questions for patients in LMICs. As a cancer community, we must continue to advocate for and work toward equitable access to high-quality interventions for patients, regardless of their geographical location.

Indexed as

Antineoplastic AgentsNeoplasmsDeveloping CountriesDrug DevelopmentHumansIncomeAntineoplastic Agents

Identifiers

PMID37944089
PMCPMC10645408

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.