Evidence map›Paper›PMID 37946883›Full record

ArticleCureus2023

Comparison of the Clinical and Metabolic Characteristics of Patients With Acute Coronary Syndromes Between the Pre- and Post-lockdown Periods.

Tommaso Capobianco, Walther Iannotti, Riccardo Agostini, Luca Persiani, Marco Chiostri, Giorgio Iacopo Baldereschi, Carlo Di Mario, Francesco Meucci, Renato Valenti, Emanuele Cecchi

Abstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tommaso CapobiancoDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Walther IannottiDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Riccardo AgostiniDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Luca PersianiDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Marco ChiostriDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Giorgio Iacopo BaldereschiDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Carlo Di MarioDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Francesco MeucciDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Renato ValentiDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.
Emanuele CecchiDepartment of Cardiac, Thoracic, and Vascular Medicine, Azienda Ospedaliero Universitaria Careggi, Florence, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn 2020, the SARS-CoV-2 pandemic outbreak required restrictive measures to limit the spread of the virus. This study aimed to assess how changes in dietary habits and lifestyle associated with such measures have affected the characteristics of patients with acute coronary syndromes (ACS) in the post-lockdown period. In particular, we evaluated if the incidence of ACS was higher in younger patients, who were more negatively affected by lockdown measures.

methodsWe analysed 609 ACS patients and compared the clinical, laboratory, and angiographic characteristics of those admitted six months before lockdown (n = 312) and those admitted in the same six-month period after lockdown. Moreover, we compared several anthropometric and laboratory data between pre- and post-lockdown in younger (≤55 years old) and older patients.

resultsThe incidence of ACS in young adults (≤55 years) was significantly higher in the post- vs. pre-lockdown period (17.5% vs. 10.9%, p = 0.019). A trend to a higher percentage of ST-elevation myocardial infarction (STEMI) was observed in the post-lockdown period together with a significantly lower incidence of non-STEMI (p = 0.033). Moreover, in the post-lockdown period, we observed in younger patients a significant increase in weight, body mass index, admission glycaemia, and triglycerides while in older patients, these parameters were significantly reduced.

conclusionThe lockdown may have negatively affected cardiovascular risk, thus increasing the incidence of ACS, particularly in younger patients who probably underwent more relevant lifestyle changes, with several consequent anthropometric and metabolic alterations. Such evidence should be considered to take preventive measures in case a new state of emergency occurs.

Indexed as

acute coronary syndromescovid-19lockdownmetabolic alterationsyoung patients

Identifiers

PMID37946883
PMCPMC10631775

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.