Evidence map›Paper›PMID 37947593›Full record

ArticleCells2023

Octopamine Rescues Endurance and Climbing Speed in

Maryam Safdar, Robert J Wessells

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Sleep regulation inFrontiers in neuroscience · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maryam SafdarDepartment of Physiology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-1123-8976
Robert J WessellsDepartment of Physiology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Wayne State University · US

Funding

Octpamine controls adaptation to endurance exercise in DrosophilaR01AG059683 · NIA · WAYNE STATE UNIVERSITY · PI Robert John Wessells · 2018 to 2026
$3.0M
Detroit Cardiovascular Training ProgramT32HL120822 · NHLBI · WAYNE STATE UNIVERSITY · PI LEVY, PHILLIP DAVID · 2014 to 2023
$1.8M
Octopamine Mediates Benefits Of Endurance Exercise In DrosophilaR21AG055712 · NIA · WAYNE STATE UNIVERSITY · PI WESSELLS, ROBERT JOHN · 2017 to 2018
$424k
NHLBI NIH HHS T32 HL120822NIA NIH HHS AG059683NIA NIH HHS R01 AG059683NIA NIH HHS R21 AG055712NINDS NIH HHS NS114558
6 · The paper itself

Abstract

Circadian rhythm disturbances are associated with various negative health outcomes, including an increasing incidence of chronic diseases with high societal costs. While exercise can protect against the negative effects of rhythm disruption, it is not available to all those impacted by sleep disruptions, in part because sleep disruption itself reduces exercise capacity. Thus, there is a need for therapeutics that bring the benefits of exercise to this population. Here, we investigate the relationship between exercise and circadian disturbances using a well-established

Indexed as

DrosophilaDrosophila ProteinsAnimalsCircadian RhythmHumansOctopaminePhenotypeDrosophila ProteinsOctopaminecircadian disruptionDrosophilaendurance exerciseoctopamine

Identifiers

PMID37947593
PMCPMC10648926
OpenAlexW4388271704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.