Evidence mapPaperPMID 37947913Full record

ReviewInflammopharmacology2023

Recent advances in anti-inflammatory active components and action mechanisms of natural medicines.

Zhimin Wu, Tao Zhang, Xiaofei Ma, Shuai Guo, Qingqing Zhou, Arshad Zahoor, Ganzhen Deng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Diverse Biological Activity of Pyrimidine Derivatives: A Review.Current drug discovery technologies · 2026
    Review
  6. Basil (Current drug discovery technologies · 2026
    Review
  7. Therapeutic Potential ofInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Zhimin WuDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Tao ZhangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei, China.
Xiaofei MaCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou, China.
Shuai GuoDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Qingqing ZhouDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Arshad ZahoorCollege of Veterinary Sciences, The University of Agriculture Peshawar, Peshawar, Pakistan.
Ganzhen DengDepartment of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China. dgz@mail.hzau.edu.cn.ORCID http://orcid.org/0000-0003-0813-927X
Huazhong Agricultural University · CNAnhui Agricultural University · CNGansu Agricultural University · CNThe University of Agriculture, Peshawar · PK

Funding

National Natural Science Foundation of China 30972744
6 · The paper itself

Abstract

Inflammation is a series of reactions caused by the body's resistance to external biological stimuli. Inflammation affects the occurrence and development of many diseases. Anti-inflammatory drugs have been used widely to treat inflammatory diseases, but long-term use can cause toxic side-effects and affect human functions. As immunomodulators with long-term conditioning effects and no drug residues, natural products are being investigated increasingly for the treatment of inflammatory diseases. In this review, we focus on the inflammatory process and cellular mechanisms in the development of diseases such as inflammatory bowel disease, atherosclerosis, and coronavirus disease-2019. Also, we focus on three signaling pathways (Nuclear factor-kappa B, p38 mitogen-activated protein kinase, Janus kinase/signal transducer and activator of transcription-3) to explain the anti-inflammatory effect of natural products. In addition, we also classified common natural products based on secondary metabolites and explained the association between current bidirectional prediction progress of natural product targets and inflammatory diseases.

Indexed as

Anti-Inflammatory AgentsBiological ProductsHumansInflammationNF-kappa BSignal TransductionAnti-Inflammatory AgentsBiological ProductsNF-kappa BAnti-inflammatoryCompoundsDrug targetInflammationNatural products

Identifiers

PMID37947913
OpenAlexW4388574350

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.