Evidence map›Paper›PMID 37948428›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2023

The everolimus eluting Synergy Megatron

Kalpa De Silva, Matthew E Li Kam Wa, Tim Wells, Abdul Mozid, Andrew Ladwiniec, Brian G Hynes, Ashish Kotecha, Karim Ratib, Sinjini Biswas, Nicolas Amabile and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Site-Specific Antithrombotic Therapy: 24-Month Outcomes of the Randomized DESyne BDS Plus Trial Using a Novel Triple-Drug Eluting Coronary Implant With Two Anticoagulants and Sirolimus.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Trial
  2. Article
  3. Management of Stent Underexpansion and Aorto-ostial Lesions.Interventional cardiology (London, England) · 2024
    Review
  4. The everolimus eluting Synergy MegatronCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 15 institutions in 3 countries.

Kalpa De SilvaCardiovascular Division, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Matthew E Li Kam WaCardiovascular Division, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0002-0091-6022
Tim WellsCardiology Department, Salisbury District Hospital, Salisbury NHS Foundation Trust, Salisbury, UK.
Abdul MozidCardio Respiratory Clinical Services Unit, Leeds General Infirmary, The Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Andrew LadwiniecDepartment of Cardiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK.
Brian G HynesCardiology Department, University Hospital Galway, Galway, Ireland.
Ashish KotechaDepartment of Cardiology, Royal Devon and Exeter Hospital, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.
Karim RatibCardiology Department, Royal Stoke University Hospital, University Hospitals of North Midlands NHS Trust, Stoke, UK.
Sinjini BiswasBristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.ORCID 0000-0003-1688-9310
Nicolas AmabileCardiology Department, L'Institut Mutualiste Montsouris, Paris, France.
Pierre DeharoCardiology Department, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Margaret McEntagartCardiology Department, Golden Jubilee Hospital, NHS Golden Jubilee, Glasgow, UK.
James C SprattCardiology Clinical Academic Group, St George's University Hospital, St George's University Hospitals NHS Foundation Trust, London, UK.ORCID 0000-0001-8719-4538
Franck DigneCardiology Department, Centre Cardiologique du Nord, Saint Denis, France.
Meadhbh HoggDepartment of Cardiology, Belfast Health and Social Care Trust, Belfast, UK.
Jonathan A MaileyDepartment of Cardiology, Belfast Health and Social Care Trust, Belfast, UK.ORCID 0000-0002-9013-5720
Simon J WalshDepartment of Cardiology, Belfast Health and Social Care Trust, Belfast, UK.
Sundeep S KalraCardiology Department, Royal Free Hospital, Royal Free London NHS Foundation Trust, London, UK.
Belfast Health and Social Care Trust · GBSt Thomas' Hospital · GBAssistance Publique Hôpitaux de Marseille · FRCentre Cardiologique du Nord · FRGlenfield Hospital · GBGolden Jubilee National Hospital · GBInstitute Mutualiste Montsouris · FRLeeds General Infirmary · GBRoyal Devon & Exeter NHS Foundation Trust · GBRoyal Free London NHS Foundation Trust · GBSalisbury District Hospital · GBSt George’s University Hospitals NHS Foundation Trust · GBUniversity Hospital Galway · IEUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity Hospitals of North Midlands NHS Trust · GB

Funding

British Heart Foundation
6 · The paper itself

Abstract

backgroundThe Synergy Megatron

aimsTo report the short- to medium-term clinical outcomes from the European Synergy Megatron

methodsThis registry was an investigator-initiated study conducted at 14 European centers. The primary outcome was target lesion failure (TLF), defined as the composite of cardiovascular death, target vessel myocardial infarction (MI), and target lesion revascularisation.

resultsFive hundred seventy-five patients underwent PCI with Megatron

conclusionsUse of the Synergy Megatron

Indexed as

Coronary Artery DiseaseDrug-Eluting StentsPercutaneous Coronary InterventionThrombosisAgedAged, 80 and overEverolimusHumansMiddle AgedRegistriesRisk FactorsTreatment OutcomeEverolimusbifurcationdrug-eluting stentleft main

Identifiers

PMID37948428
PMCPMC10903108
OpenAlexW4388564154

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.