Statins × adverse events & safety

SynthesisLipids in health and disease2023

The association of statin therapy and cancer: a meta-analysis.

Zijian Chen et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 2023

Range includes no effect

No clear effect on adverse events & safety

−1%−5% to +3%

Smaller than almost all for adverse events & safety

As reported

OR 0.99, 95% CI 0.95–1.03

Range includes no effect

No clear effect on adverse events & safety

−1%−9% to +7%

Smaller than almost all for adverse events & safety

As reported

OR 0.99, 95% CI 0.91–1.07

Two numbers in the abstract

the abstract, start to end

with statins compared to placebo [OR = 0.99, 95% CI (0.95, 1.03)].

did not decrease cancer mortality [OR = 0.99, 95% CI (0.91, 1.07)].

← favours treatmentfavours comparator →
could be chance
Adverse events & safety
OR 0.990.95–1.03
Adverse events & safety
OR 0.990.91–1.07
StatinsAdverse events & safety

Statins × adverse events & safetyharms?mixed

unlikelylikely
0.16not counted
← favours comparatorfavours treatment →
more certainless certain
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23 papers cite it

2023
2024
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2026
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Full record →Abstract, authors, funding and every citing paper · PMID 37950285