Evidence map›Paper›PMID 37958695›Full record

ArticleInternational journal of molecular sciences2023

A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with

Jules Cretin, Mathieu Adjemout, Christelle Dieppois, Frederic Gallardo, Magali Torres, Zachary Merard, Serge Aimé Sawadogo, Christophe Picard, Pascal Rihet, Pascale Paul

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jules CretinINSERM 1090, TAGC Theories and Approaches of Genomic Complexity, Campus de Luminy, Aix Marseille University, 13288 Marseille, France.
Mathieu AdjemoutINSERM 1090, TAGC Theories and Approaches of Genomic Complexity, Campus de Luminy, Aix Marseille University, 13288 Marseille, France.
Christelle DieppoisINSERM 1090, TAGC Theories and Approaches of Genomic Complexity, Campus de Luminy, Aix Marseille University, 13288 Marseille, France.
Frederic GallardoINSERM 1090, TAGC Theories and Approaches of Genomic Complexity, Campus de Luminy, Aix Marseille University, 13288 Marseille, France.
Magali TorresINSERM 1090, TAGC Theories and Approaches of Genomic Complexity, Campus de Luminy, Aix Marseille University, 13288 Marseille, France.
Zachary MerardADES UMR, Aix Marseille University, 13288 Marseille, France.
Serge Aimé SawadogoUnité de Formation en Sciences de la Santé (UFR/SDS), Université Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso.
Christophe PicardADES UMR, Aix Marseille University, 13288 Marseille, France.
Pascal RihetINSERM 1090, TAGC Theories and Approaches of Genomic Complexity, Campus de Luminy, Aix Marseille University, 13288 Marseille, France.ORCID 0000-0002-9459-3905
Pascale PaulINSERM 1090, TAGC Theories and Approaches of Genomic Complexity, Campus de Luminy, Aix Marseille University, 13288 Marseille, France.ORCID 0000-0002-6734-4479
Inserm · FRAix-Marseille Université · FR

Funding

Délégation Régionale Provence-Alpes-Côte d'Azur et Corse Institutional funding no grant number
6 · The paper itself

Abstract

Antibodies play a crucial role in activating protective immunity against malaria by interacting with Fc-gamma receptors (FcγRs). Genetic variations in genes encoding FcγRs can affect immune cell responses to the parasite. In this study, our aim was to investigate whether non-coding variants that regulate FcγR expression could influence the prevalence of

Indexed as

Malaria, FalciparumReceptors, IgGAdultBurkina FasoChildHumansMultigene FamilyPlasmodium falciparumFCGR1A protein, humanReceptors, IgGBurkina FasoFc-gamma receptor (FCGR) gene polymorphismFc-gamma receptors/FcγRsFCGR2A gene polymorphismFCGR2B gene polymorphismFCGR ex-pression quantitative trait loci (eQTL)malariaPlasmodium falciparum parasitemiaregulatory variants

Identifiers

PMID37958695
PMCPMC10650193
OpenAlexW4388158832

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.