Evidence map›Paper›PMID 37959778›Full record

ArticleMolecules (Basel, Switzerland)2023

Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury.

Viacheslav V Andrianov, Vladimir A Kulchitsky, Guzel G Yafarova, Leah V Bazan, Tatiana K Bogodvid, Irina B Deryabina, Lyudmila N Muranova, Dinara I Silantyeva, Almaz I Arslanov, Mikhail N Paveliev and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Evaluation of Nitric Oxide-Donating Properties of 11Molecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Viacheslav V AndrianovZavoisky Physical-Technical Institute of the Russian Academy of Sciences, 420000 Kazan, Russia.
Vladimir A KulchitskyBrain Center, Institute of Physiology, National Academy of Sciences, 220012 Minsk, Belarus.
Guzel G YafarovaZavoisky Physical-Technical Institute of the Russian Academy of Sciences, 420000 Kazan, Russia.
Leah V BazanZavoisky Physical-Technical Institute of the Russian Academy of Sciences, 420000 Kazan, Russia.
Tatiana K BogodvidDepartment of Human and Animals, Institute of Fundamental Medicine and Biology, Kazan Federal University, 420000 Kazan, Russia.
Irina B DeryabinaDepartment of Human and Animals, Institute of Fundamental Medicine and Biology, Kazan Federal University, 420000 Kazan, Russia.
Lyudmila N MuranovaDepartment of Human and Animals, Institute of Fundamental Medicine and Biology, Kazan Federal University, 420000 Kazan, Russia.
Dinara I SilantyevaDepartment of Human and Animals, Institute of Fundamental Medicine and Biology, Kazan Federal University, 420000 Kazan, Russia.
Almaz I ArslanovDepartment of Human and Animals, Institute of Fundamental Medicine and Biology, Kazan Federal University, 420000 Kazan, Russia.
Mikhail N PavelievNeuroscience Center, University of Helsinki, 00014 Helsinki, Finland.
Ekaterina V FedorovaBrain Center, Institute of Physiology, National Academy of Sciences, 220012 Minsk, Belarus.
Tatiana A FilipovichBrain Center, Institute of Physiology, National Academy of Sciences, 220012 Minsk, Belarus.
Aleksei V NagibovBrain Center, Institute of Physiology, National Academy of Sciences, 220012 Minsk, Belarus.
Khalil L GainutdinovZavoisky Physical-Technical Institute of the Russian Academy of Sciences, 420000 Kazan, Russia.
Kazan Federal University · RUInstitute of Physiology National Academy of Sciences of Belarus · BYKazan E. K. Zavoisky Physical-Technical Institute · RUUniversity of Helsinki · FI

Funding

Belarusian Republican Foundation for Fundamental Research M23RNF-067Russian Science Foundation 23-45-10004
6 · The paper itself

Abstract

Nitric oxide (NO) production in injured and intact brain regions was compared by EPR spectroscopy in a model of brain and spinal cord injury in Wistar rats. The precentral gyrus of the brain was injured, followed by the spinal cord at the level of the first lumbar vertebra. Seven days after brain injury, a reduction in NO content of 84% in injured brain regions and 66% in intact brain regions was found. The difference in NO production in injured and uninjured brain regions persisted 7 days after injury. The copper content in the brain remained unchanged one week after modeling of brain and spinal cord injury. The data obtained in the experiments help to explain the problems in the therapy of patients with combined brain injury.

Indexed as

Brain InjuriesSpinal Cord InjuriesAnimalsBrainHumansNitric OxideRatsRats, WistarSpinal CordNitric Oxidebrain strokecooperelectron paramagnetic resonancenitric oxidespinal cord injury

Identifiers

PMID37959778
PMCPMC10650517
OpenAlexW4388048865

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.