Evidence map›Paper›PMID 37961283›Full record

ArticleResearch square2023

Mechanical Evaluation of Frozen and Cryo-Sectioned Papillary Muscle Samples by Using Sinusoidal Analysis: Cross-bridge Kinetics and the Effect of Partial Ca

Jing Xi, Han-Zhong Feng, Jian-Ping Jin, Jinxiang Yuan, Masataka Kawai

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jing XiSchool of Nursing, and Medical Skill Experiment Teaching Center, Suzhou Medical College, Soochow University, Suzhou 215006, China.
Han-Zhong FengDept of Physiology and Biophysics, Univ of Illinois at Chicago, 835 S Wolcot Ave, Chicago, IL 60612, USA.
Jian-Ping JinDept of Physiology and Biophysics, Univ of Illinois at Chicago, 835 S Wolcot Ave, Chicago, IL 60612, USA.
Jinxiang YuanThe Collaborative Innovation Center, Jining Medical University, Jining, 272067, China.
Masataka KawaiDepartment of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
University of Iowa · USJining Medical University · CNSoochow University · CN

Funding

Regulation of Troponin I in Cardiac Adaptation & FailureR01HL127691 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2016 to 2026
$3.5M
NHLBI NIH HHS R01 HL127691
6 · The paper itself

Abstract

The use of frozen and cryo-sectioned cardiac muscle preparations, introduced recently by (Feng & Jin, 2020), offers promising advantages of easy transport and exchange of muscle samples among collaborating laboratories. In this report, we examined integrity of such preparation by studying tension transients in response to sinusoidal length changes and following concomitant amplitude and phase shift in tension time courses at varying frequencies. We used sections with 70 μm thickness, isolated fiber preparations, and studied cross-bridge (CB) kinetics: we activated the preparations with saturating Ca

Identifiers

PMID37961283
PMCPMC10635403
OpenAlexW4388130610

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.