ArticleScience signaling2023
Impaired intracellular Ca
Open access · greenAbstract read
In one paragraph
Article in Science signaling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 17 citations in OpenAlex.
- Neurovascular coupling in the basolateral amygdala modulates negative emotions.Cell research · 2026Article
- The nonexcitable smooth muscle: remodeling the smooth muscle ion transport toolkit in disease.Physiological reviews · 2026Review
- Potassium channels in vascular smooth muscle cells.Physiological reviews · 2026Review
- TRPM4 Couples Mechanical Force to Myogenic Constriction Throughout the Resistance Vasculature.bioRxiv : the preprint server for biology · 2026Article
- Age-dependent vascular and neurological characteristics of CADASIL are recapitulated in Notch3 mutant zebrafish, implicating a role for type IV collagen in disease progression.Acta neuropathologica communications · 2026Article
- Multi-omics reveals key cell types and gene families regulating eggshell strength in chicken uteri.Zoological research · 2025Article
- Collagen IV in Gould syndrome and Alport syndrome.Nature reviews. Nephrology · 2025Review
- The pathogenesis of cerebral small vessel disease and vascular cognitive impairment.Physiological reviews · 2025Review
- Role of the Renin-Angiotensin System in Blood Pressure Regulation in Smooth Muscle-Specific Cullin-3 Deficient Mice.Hypertension (Dallas, Tex. : 1979) · 2025Article
- A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome.The Journal of cell biology · 2025Article
- Transient Receptor Potential Channels in Vascular Mechanotransduction.American journal of hypertension · 2025Review
- Multimodal neuroimaging ofFrontiers in neuroscience · 2025Article
- Skeletal pathology in mouse models of Gould syndrome is partially alleviated by genetically reducing TGFβ signaling.Matrix biology : journal of the International Society for Matrix Biology · 2024Article
- Evaluating neural crest cell migration in a Col4a1 mutant mouse model of ocular anterior segment dysgenesis.Cells & development · 2024Article
- Pathophysiology of cerebral small vessel disease: a journey through recent discoveries.The Journal of clinical investigation · 2024Review
- Functional, Structural and Proteomic Effects of Ageing in Resistance Arteries.International journal of molecular sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Evan YamasakiDepartment of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, NV 89557-0318, USA.ORCID 0000-0001-9052-039X
Pratish ThakoreDepartment of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, NV 89557-0318, USA.
Sher AliDepartment of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, NV 89557-0318, USA.
Alfredo Sanchez SolanoDepartment of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, NV 89557-0318, USA.
Xiaowei WangDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, CA 94158, USA.
Xiao GaoDepartment of Physical Therapy and Rehabilitation Science, UCSF School of Medicine, San Francisco, CA 94143, USA.
Cassandre Labelle-DumaisDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, CA 94158, USA.
Myriam M ChaumeilDepartment of Physical Therapy and Rehabilitation Science, UCSF School of Medicine, San Francisco, CA 94143, USA.
Douglas B GouldDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, CA 94158, USA.
Scott EarleyDepartment of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, NV 89557-0318, USA.
University of California, San Francisco · USUniversity of Nevada, Reno · US
Funding
Transgenic Animal Genotyping and Phenotyping CoreP20GM130459 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Yumei Feng Earley · 2019 to 2026
$20.3MRapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ULLIAN, ERIK M · 1985 to 2024
$16.8MTRP channels as fundamental sensors of the cerebral microcirculationR35HL155008 · NHLBI · UNIVERSITY OF ROCHESTER · PI Scott Earley · 2021 to 2026
$5.5MTRP Channel-Dependent Regulation of Arterial Tone (Renewal)R01HL091905 · NHLBI · UNIVERSITY OF NEVADA RENO · PI EARLEY, SCOTT · 2009 to 2020
$5.1MThe Neural Mechanisms of HypertensionR01HL122770 · NHLBI · UNIVERSITY OF ROCHESTER · PI FENG EARLEY, YUMEI · 2015 to 2023
$4.2MMechanisms of Functional Vascular Impairment In Genetic Models of Cerebral Small Vessel DiseaseRF1NS110044 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EARLEY, SCOTT, GOULD, DOUGLAS · 2018 to 2022
$3.3MDiversity Supplement-MassoudiR33NS115132 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAUMEIL, MYRIAM MARIANNE, EARLEY, SCOTT · 2021 to 2023
$2.6MSensory mechanisms in brain capillary endothelial cells that initiate functional hyperemiaR01HL139585 · NHLBI · UNIVERSITY OF NEVADA RENO · PI EARLEY, SCOTT · 2018 to 2020
$1.7MStructural Basis of Peripheral Coupling Sites Regulating Arterial Smooth Muscle Contractility (A1)R01HL137852 · NHLBI · UNIVERSITY OF NEVADA RENO · PI EARLEY, SCOTT · 2018 to 2020
$1.6MNEI NIH HHS P30 EY002162NHLBI NIH HHS R01 HL091905NHLBI NIH HHS R01 HL122770NHLBI NIH HHS R01 HL137852NHLBI NIH HHS R01 HL139585NHLBI NIH HHS R35 HL155008NIGMS NIH HHS P20 GM130459NINDS NIH HHS R33 NS115132NINDS NIH HHS RF1 NS110044
Abstract
Humans and mice with mutations in
Indexed as
Signal TransductionTRPM Cation ChannelsAnimalsCollagen Type IVHumansIon TransportMiceVasoconstrictionCol4a1 protein, mouseCollagen Type IVTRPM4 protein, mouseTRPM Cation Channels
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.