Evidence map›Paper›PMID 37969556›Full record

ArticleCJC pediatric and congenital heart disease2022

Medical Management of Infants With Supraventricular Tachycardia: Results From a Registry and Review of the Literature.

Nathan Wei, Avani Lamba, Sonia Franciosi, Ian H Law, Luis A Ochoa, Christopher L Johnsrude, Sit Yee Kwok, Teng Hong Tan, Santokh S Dhillon, Anne Fournier and 8 more

Erratum issuedAbstract read
In one paragraph

Article in CJC pediatric and congenital heart disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Landiolol is effective and safe in paediatric supraventricular tachycardia: evidence from a European prospective multicentre open-label phase III study (LANDI-PED).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Trial
  3. Practical compendium of antiarrhythmic drugs: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. CJC pediatric and congenital heart disease · 2022
    Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Nathan WeiBC Children's Hospital, Division of Cardiology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
Avani LambaBC Children's Hospital, Division of Cardiology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
Sonia FranciosiBC Children's Hospital, Division of Cardiology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
Ian H LawDepartment of Pediatrics, Division of Pediatric Cardiology, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa, USA.
Luis A OchoaDepartment of Pediatrics, Division of Pediatric Cardiology, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa, USA.
Christopher L JohnsrudeDivision of Pediatric Cardiology, Department of Pediatrics, University of Louisville, Louisville, Kentucky, USA.
Sit Yee KwokDepartment of Pediatric Cardiology, Queen Mary Hospital, Hong Kong, Hong Kong.
Teng Hong TanCardiology Service, Department of Pediatric Subspecialties, KK Women's and Children's Hospital, Singapore, Singapore.
Santokh S DhillonDivision of Cardiology, Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada.
Anne FournierDivision of Pediatric Cardiology, Department of Pediatrics, CHU Ste Justine Hospital, Montreal, Québec, Canada.
Stephen P SeslarDepartment of Pediatrics, Division of Cardiology, Seattle Children's Hospital, Seattle, Washington, USA.
Elizabeth A StephensonLabbatt Family Heart Centre, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Andrew D BlaufoxDepartment of Pediatrics, Division of Pediatric Cardiology, Cohen Children's Medical Center of New York, New Hyde Park, New York, USA.
Michel Cabrera OrtegaDepartment of Arrhythmia and Cardiac Pacing, Cardiocentro Pediatrico William Soler, Havana, Cuba.
Jeffrey N BoneResearch Informatics, British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Ash SandhuResearch Informatics, British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Carolina A EscuderoDepartment of Pediatrics, Division of Pediatric Cardiology, University of Alberta, Stollery Children's Hospital, Edmonton, Alberta, Canada.
Shubhayan SanataniBC Children's Hospital, Division of Cardiology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several medication choices are available for acute and prophylactic treatment of refractory supraventricular tachycardia (SVT) in infants. There are almost no controlled trials, and medication choices are not necessarily evidence based. Our objective was to report the effectiveness of management strategies for infant SVT. Methods: A registry of infants admitted to hospital with re-entrant SVT and no haemodynamically significant heart disease were prospectively followed at 11 international tertiary care centres. In addition, a systematic review of studies on infant re-entrant SVT in MEDLINE and EMBASE was conducted. Data on demographics, symptoms, acute and maintenance treatments, and outcomes were collected. Results: A total of 2534 infants were included: n = 108 from the registry (median age, 9 days [0-324 days], 70.8% male) and n = 2426 from the literature review (median age, 14 days; 62.3% male). Propranolol was the most prevalent acute (61.4%) and maintenance treatment (53.8%) in the Registry, whereas digoxin was used sparingly (4.0% and 3.8%, respectively). Propranolol and digoxin were used frequently in the literature acutely (31% and 33.2%) and for maintenance (17.8% and 10.1%) ( Conclusion: This was the largest cohort of infants with SVT analysed to date. Digoxin monotherapy use was rare amongst contemporary paediatric cardiologists. There was limited evidence to support one medication over another. Overall, recurrence and mortality rates on antiarrhythmic treatment were low.

Identifiers

PMID37969556
PMCPMC10642123

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.