Trial reportDiabetologia2024
Early time-restricted carbohydrate consumption vs conventional dieting in type 2 diabetes: a randomised controlled trial.
Trial report in Diabetologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05713058 (Effects of Early Time-restricted Carbohydrate Consumption on Weight Loss and Glucose Homeostasis in Patients With Type 2 Diabetes), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Early Time-restricted Carbohydrate Consumption on Weight Loss and Glucose Homeostasis in Patients With Type 2 Diabetes
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Effects of time-restricted eating on metabolic panel and sleep profile in patients with type 2 diabetes: a meta-analysis.Frontiers in nutrition · 2026Pooled it
- Comparative efficacy of dietary interventions for overweight or obese adults with type 2 diabetes: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in nutrition · 2026Pooled it
- Trial
- The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology.Journal of advanced research · 2026Review
- A Novel Chronotype-Based Mediterranean Diet Pyramid: An Updated Representation by the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI).Current nutrition reports · 2026Review
- Personalized Optimal Fat Intake for Glycemic Health: Evidence of a U-Shaped Association and Heterogeneity From NHANES.Journal of diabetes research · 2026Article
- Circadian nutrition and obesity: timing as a nutritional strategy.Journal of health, population, and nutrition · 2025Review
- Chrononutrition and Diabetes: Mapping the Scientific Landscape Through Bibliometric Insights.Cureus · 2025Review
- Postprandial hypoglycaemia after gastric bypass in type 2 diabetes: pathophysiological mechanisms and clinical implications.Diabetologia · 2025Article
- Insights in Nutrition to Optimize Type 1 Diabetes Therapy.Nutrients · 2024Review
- Review
- Cautious Optimism Warranted for Stem Cell-Derived Islet Transplantation in Type 2 Diabetes.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 2 countries.
Funding
Abstract
aims/hypothesisEarly time-restricted carbohydrate consumption (eTRC) is a novel dietary strategy that involves restricting carbohydrate-rich food intake to the morning and early afternoon to align with circadian variations in glucose tolerance. We examined the efficacy, feasibility and safety of eTRC in individuals with type 2 diabetes under free-living conditions.
methodsIn this randomised, parallel-arm, open label, controlled trial, participants with type 2 diabetes and overweight/obesity (age 67.2±7.9 years, 47.8% women, BMI 29.4±3.7 kg/m
resultsTwelve (85.7%) participants in the eTRC arm and 11 (84.6%) participants in the control arm completed the study, achieving similar reductions in body weight and fat mass. The two groups experienced comparable improvements in HbA CONCLUSIONS/
interpretationThe proposed eTRC diet provides a feasible and effective alternative option for glucose and body weight management in individuals with type 2 diabetes, with no additional metabolic benefits compared with conventional dieting.
trial registrationClinicalTrials.gov NCT05713058
fundingThis study was supported by the European Society for Clinical Nutrition and Metabolism (ESPEN) and the Italian Society of Diabetology (SID).
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.