ArticleProceedings of the National Academy of Sciences of the United States of America2023
A peptidomimetic modulator of the Ca
Open access · greenAbstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Advances in orofacial pain research: a bibliometric analysis.Frontiers in neurology · 2025Pooled it
- Spared but Not Silent: Ion Channel Plasticity in Uninjured Sensory Neurons in Neuropathic Pain.International journal of molecular sciences · 2026Review
- Article
- Parabrachial bombesin receptor subtype 3 neurons facilitate heat hypersensitivity in persistent pain.bioRxiv : the preprint server for biology · 2026Article
- Targeting CRMP2 for Chronic Pain: From Molecular Mechanisms to Therapeutic Strategies.Biomedicines · 2026Review
- Enhancement of Calcium Ion Permeation via Resonant Coupling of Ion and Terahertz Waves in Voltage Gated Calcium Channels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice.Journal of inflammation research · 2026Article
- Article
- Recent advances in the pharmacology of voltage-gated ion channels.Pharmacological reviews · 2025Review
- Distinct nucleus accumbens neural pathways underlie separate behavioral features of chronic pain and comorbid depression.The Journal of clinical investigation · 2025Article
- Beyond single targets: leveraging degeneracy in sodium channels for osteoarthritis analgesia.Pain reports · 2025Article
- Degradation of voltage-gated calcium channels: mechanisms and applications in neurological and cardiovascular diseases.Cell communication and signaling : CCS · 2025Review
- Lanthionine Ketimine Ethyl Ester Induces Proliferation and Maturation and Regulates Calcium Flux in Primary Mouse Oligodendrocyte Progenitor Cells.Journal of neuroscience research · 2025Article
- Mouse models of non-dystrophic and dystrophic myotonia exhibit nociplastic pain-like behaviors.bioRxiv : the preprint server for biology · 2025Article
- Voltage-Gated Ion Channels in Neuropathic Pain Signaling.Life (Basel, Switzerland) · 2025Review
- SUMOylation and DeSUMOylation: Tug of War of Pain Signaling.Molecular neurobiology · 2025Review
- Regulatory Action of Calcium and Calcium Channels in Pain Pathways.International journal of biological sciences · 2025Review
- Decoding pain chronification: mechanisms of the acute-to-chronic transition.Frontiers in molecular neuroscience · 2025Review
- Article
- Uncoupling the CRMP2-CaThe journal of pain · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
37 authors at 10 institutions in 2 countries.
Kimberly Gomez *Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.ORCID 0000-0003-1867-5041
Ulises Santiago *Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15261.
Tyler S NelsonDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
Heather N AllenDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
Aida Calderon-RiveraDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.ORCID 0000-0002-0129-2848
Sara HestehaveDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.ORCID 0000-0002-1837-521X
Erick J Rodríguez PalmaDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.ORCID 0000-0002-9940-363X
Yuan ZhouDepartment of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ 85724.
Paz DuranDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.ORCID 0000-0001-8729-8636
Santiago Loya-LopezDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
Elaine ZhuDepartment of Anesthesiology, Perioperative Care and Pain Medicine, New York University Grossman School of Medicine, New York, NY 10016.ORCID 0000-0003-2690-9100
Upasana KumarDepartment of Diagnostic Sciences, Center for Orofacial Pain and Temporomandibular Disorders, Rutgers School of Dental Medicine, Newark, NJ 07101.ORCID 0000-0002-2350-9374
Rory ShieldsRutgers School of Graduate Studies, Newark Health Science Campus, Newark, NJ 07101.
Eda KoseliDepartment of Pharmacology and Toxicology and Translational Research Initiative for Pain and Neuropathy, Virginia Commonwealth University, Richmond, VA 23298.ORCID 0000-0002-4812-4024
Bryan McKiverDepartment of Pharmacology and Toxicology and Translational Research Initiative for Pain and Neuropathy, Virginia Commonwealth University, Richmond, VA 23298.ORCID 0000-0002-1447-5803
Denise GiuvelisDepartment of Biomedical Sciences, College of Osteopathic Medicine, Center for Excellence in the Neurosciences, University of New England, Biddeford, ME 04005.
Wanhong ZuoDepartment of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ 07103.
Kufreobong E InyangDepartment of Physiology, Michigan State University, East Lansing, MI 48824.ORCID 0000-0002-0735-6945
Angie DorameDepartment of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ 85724.
Aude ChefdevilleDepartment of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ 85724.
Dongzhi RanDepartment of Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Samantha Perez-MillerDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
Yi LuDepartment of Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Xia LiuDepartment of Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
HandokoDepartment of Chemistry, New York University, New York, NY 10003.ORCID 0000-0002-4433-3080
Paramjit S AroraDepartment of Chemistry, New York University, New York, NY 10003.ORCID 0000-0001-5315-401X
Marcel PatekBright Rock Path Limited Liability Company, Tucson, AZ 85724.ORCID 0000-0002-2512-9252
Aubin MoutalDepartment of Pharmacology and Physiology, School of Medicine, St. Louis University, St. Louis, MO 63104.
May KhannaDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.ORCID 0000-0002-9989-6374
Huijuan HuDepartment of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ 07103.ORCID 0000-0003-2306-2514
Geoffroy LaumetDepartment of Physiology, Michigan State University, East Lansing, MI 48824.ORCID 0000-0001-6752-3592
Tamara KingDepartment of Biomedical Sciences, College of Osteopathic Medicine, Center for Excellence in the Neurosciences, University of New England, Biddeford, ME 04005.
Jing WangDepartment of Anesthesiology, Perioperative Care and Pain Medicine, New York University Grossman School of Medicine, New York, NY 10016.
M Imad DamajDepartment of Pharmacology and Toxicology and Translational Research Initiative for Pain and Neuropathy, Virginia Commonwealth University, Richmond, VA 23298.
Olga A KorczeniewskaDepartment of Diagnostic Sciences, Center for Orofacial Pain and Temporomandibular Disorders, Rutgers School of Dental Medicine, Newark, NJ 07101.ORCID 0000-0001-8399-794X
Carlos J CamachoDepartment of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15261.ORCID 0000-0003-1741-8529
Rajesh KhannaDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.ORCID 0000-0002-9066-2969
New York University · USRutgers, The State University of New Jersey · USChongqing Medical University · CNUniversity of Arizona · USVirginia Commonwealth University · USMichigan State University · USNYU Langone Health · USUniversity of New England · USUniversity of Pittsburgh · USSaint Louis University · US
Funding
Pilot Project ProgramP30GM145497 · NIGMS · UNIVERSITY OF NEW ENGLAND · PI IAN D MENG · 2022 to 2026
$6.6MCentral glutamate signaling in postoperative pain regulation - Revision - 1R01GM115384 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Jing Wang · 2015 to 2026
$5.4MVirginia Commonwealth University Initiative for Maximizing Student DevelopmentR25GM090084 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI AKBARALI, HAMID I, LLOYD, JOYCE A. · 2010 to 2022
$5.2MCRMP2, mitochondria, and Huntington’s diseaseR01NS098772 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI BRUSTOVETSKY, NICKOLAY, KHANNA, RAJESH · 2017 to 2021
$2.8MSentrin proteases, CRMP2 deSUMOylation, and Chronic PainR01NS120663 · NINDS · UNIVERSITY OF FLORIDA · PI KHANNA, RAJESH · 2020 to 2021
$2.6MExploring CRMP5 as a novel target for Alzheimers diseaseR01NS119263 · NINDS · UNIVERSITY OF ARIZONA · PI Aubin Moutal · 2021 to 2026
$2.2MNeuroimmune interactions regulating the balance between remission and relapse of painR01NS121259 · NINDS · MICHIGAN STATE UNIVERSITY · PI LAUMET, GEOFFROY O · 2021 to 2025
$2.0MCortical information integration as a model for pain perception and behaviorRF1NS121776 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, ZHE SAGE, WANG, JING · 2021 to 2021
$2.0MCRMP2, Nav1.7 sodium channel, and chronic painR01DA042852 · NIDA · UNIVERSITY OF ARIZONA · PI KHANNA, RAJESH · 2017 to 2021
$1.9MCortical Information Integration as a Model for Pain Perception and BehaviorR01NS121776 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, ZHE SAGE, WANG, JING · 2024 to 2025
$1.2M(PQ12) Peroxisome proliferator-activated receptor alpha agonists as potential treatment for chemotherapy-induced peripheral neuropathyR01CA219637 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI DAMAJ, M. IMAD, GEWIRTZ, DAVID A. · 2018 to 2021
$1.2MVCU Initiative for Maximizing Student Development Program (IMSD)T32GM148403 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI AKBARALI, HAMID I, ESCALANTE, CARLOS R · 2023 to 2025
$647kNCI NIH HHS R01 CA219637NIDA NIH HHS R01 DA042852NIGMS NIH HHS GM115384NIGMS NIH HHS P30 GM145497NIGMS NIH HHS P30GM145497NIGMS NIH HHS R01 GM115384NIGMS NIH HHS R25 GM090084NIGMS NIH HHS T32 GM148403NINDS NIH HHS F32 NS128392NINDS NIH HHS K00 NS124190NINDS NIH HHS R01 NS098772NINDS NIH HHS R01 NS119263NINDS NIH HHS R01 NS120663NINDS NIH HHS R01 NS121259NINDS NIH HHS R01 NS121776NINDS NIH HHS RF1 NS121776
Abstract
Transmembrane Ca
Indexed as
Chronic PainPeptidomimeticsAnimalsCalciumCalcium Channels, N-TypeGanglia, SpinalRatsRats, Sprague-DawleySensory Receptor CellsCalciumCalcium Channels, N-TypePeptidomimeticsanalgesiaCav2.2chronic painelectrophysiologypeptidomimetic
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.