Evidence map›Paper›PMID 37974470›Full record

ReviewEuropean psychiatry : the journal of the Association of European Psychiatrists2023

A systematic meta-review of systematic reviews on attention deficit hyperactivity disorder.

Ashmita Chaulagain, Ingvild Lyhmann, Anne Halmøy, Tarjei Widding-Havneraas, Olav Nyttingnes, Ingvar Bjelland, Arnstein Mykletun

Abstract readReview
In one paragraph

Review in European psychiatry : the journal of the Association of European Psychiatrists, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Psychiatric diagnosis on the edge: is there evidence of benefit?European child & adolescent psychiatry · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. [Graph convolution-based brain network analysis of visual mismatch negativity in adults with attention-deficit/hyperactivity disorder].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashmita ChaulagainCentre for Research and Education in Forensic Psychiatry, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0001-5467-181X
Ingvild LyhmannCentre for Research and Education in Forensic Psychiatry, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0003-1376-1354
Anne HalmøyDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-2020-6164
Tarjei Widding-HavneraasCentre for Research and Education in Forensic Psychiatry, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-5823-7508
Olav NyttingnesCentre for Research and Education in Forensic Psychiatry, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0003-0991-7176
Ingvar BjellandDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-1113-8323
Arnstein MykletunCentre for Research and Education in Forensic Psychiatry, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-3878-0079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are now hundreds of systematic reviews on attention deficit hyperactivity disorder (ADHD) of variable quality. To help navigate this literature, we have reviewed systematic reviews on any topic on ADHD.

methodsWe searched MEDLINE, PubMed, PsycINFO, Cochrane Library, and Web of Science and performed quality assessment according to the Joanna Briggs Institute Manual for Evidence Synthesis. A total of 231 systematic reviews and meta-analyses met the eligibility criteria.

resultsThe prevalence of ADHD was 7.2% for children and adolescents and 2.5% for adults, though with major uncertainty due to methodological variation in the existing literature. There is evidence for both biological and social risk factors for ADHD, but this evidence is mostly correlational rather than causal due to confounding and reverse causality. There is strong evidence for the efficacy of pharmacological treatment on symptom reduction in the short-term, particularly for stimulants. However, there is limited evidence for the efficacy of pharmacotherapy in mitigating adverse life trajectories such as educational attainment, employment, substance abuse, injuries, suicides, crime, and comorbid mental and somatic conditions. Pharmacotherapy is linked with side effects like disturbed sleep, reduced appetite, and increased blood pressure, but less is known about potential adverse effects after long-term use. Evidence of the efficacy of nonpharmacological treatments is mixed.

conclusionsDespite hundreds of systematic reviews on ADHD, key questions are still unanswered. Evidence gaps remain as to a more accurate prevalence of ADHD, whether documented risk factors are causal, the efficacy of nonpharmacological treatments on any outcomes, and pharmacotherapy in mitigating the adverse outcomes associated with ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityCentral Nervous System StimulantsSuicideAdolescentAdultChildHumansSystematic Reviews as TopicCentral Nervous System StimulantsADHDChild and adolescent psychiatryEpidemiologyPublic HealthSystematic reviews

Identifiers

PMID37974470
PMCPMC10755583

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.