Evidence map›Paper›PMID 37975253›Full record

ArticleOncology reports2024

β‑carotene attenuates muscle wasting in cancer cachexia by regulating myogenesis and muscle atrophy.

Yerin Kim, Yeonsoo Oh, Yoo Sun Kim, Jae-Ho Shin, Yeon Su Lee, Yuri Kim

Open access · hybridAbstract read
In one paragraph

Article in Oncology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Biomolecules & therapeutics · 2025
    Article
  4. Exploring heterogeneity: a dive into preclinical models of cancer cachexia.American journal of physiology. Cell physiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Yerin KimDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Republic of Korea.
Yeonsoo OhDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Republic of Korea.
Yoo Sun KimDevelopmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Jae-Ho ShinDepartment of Biomedical Laboratory Science, Eulji University, Gyeonggi‑do 13135, Republic of Korea.
Yeon Su LeeDepartment of Biomedical Laboratory Science, Eulji University, Gyeonggi‑do 13135, Republic of Korea.
Yuri KimDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Republic of Korea.
Eulji University · KRNational Cancer Institute · USEwha Womans University · KRNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cachexia is a metabolic disease involving multiple organs, which is accompanied by the depletion of muscle tissue and is associated with ~20% of cancer‑related deaths. Muscle wasting is a critical factor in cancer cachexia. β‑carotene (BC) has been shown to increase muscle mass and hypertrophy in healthy mice. However, its effects on muscle tissue dysregulation in cancer cachexia have yet to be studied. In the present study, 5‑week‑old male C57BL/6J mice were injected with 1x10

Indexed as

CachexiaCarcinoma, Lewis LungAnimalsbeta CaroteneCulture Media, ConditionedCytokinesMaleMiceMice, Inbred C57BLMuscle DevelopmentMuscle Fibers, SkeletalMuscle, SkeletalMuscular AtrophyPhosphatidylinositol 3-KinasesSignal Transductionbeta CaroteneCulture Media, ConditionedCytokinesPhosphatidylinositol 3-Kinasescancer cachexiamuscle atrophymuscle wastingmyogenesisβ‑carotene

Identifiers

PMID37975253
PMCPMC10696564
OpenAlexW4388734504

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.