Evidence map›Paper›PMID 37986065›Full record

ReviewCancer cell international2023

Recent advances on high-efficiency of microRNAs in different types of lung cancer: a comprehensive review.

Mohammad Saleh Sadeghi, Mohadeseh Lotfi, Narges Soltani, Elahe Farmani, Jaime Humberto Ortiz Fernandez, Sheida Akhlaghitehrani, Safaa Hallol Mohammed, Saman Yasamineh, Hesam Ghafouri Kalajahi, Omid Gholizadeh

Open access · goldAbstract readReview
In one paragraph

Review in Cancer cell international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. MiRNA Dysregulation in Brain Injury: AnCurrent neuropharmacology · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Mohammad Saleh SadeghiDepartment of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Mohadeseh LotfiSchool of Medicine, Tehran University of Medical Science, Tehran, Iran.
Narges SoltaniSchool of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
Elahe FarmaniTehran University of Medical Sciences, Tehran, Iran.
Jaime Humberto Ortiz FernandezUniversidad Peruana Los Andes, Huancayo, Peru.
Sheida AkhlaghitehraniFaculty of Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.
Safaa Hallol MohammedCollage of Pharmacy, National University of Science and Technology, Dhi Qar, Iraq.
Saman YasaminehFree Researcher, Viro & Biotech, Tehran, Iran. Yassaman124@gmail.com.
Hesam Ghafouri KalajahiDepartment of Biotechnology, Institute of Science, Uskudar University, Istanbul, Turkey.
Omid GholizadehFree Researcher, Viro & Biotech, Tehran, Iran. ogholizade1374@gmail.com.
Tehran University of Medical Sciences · IRLos Andes Peruvian University · PEThi Qar University · IQUniversity of Rome Tor Vergata · ITUniversity of Tehran · IRÜsküdar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carcinoma of the lung is among the most common types of cancer globally. Concerning its histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer (SCLC) subtype. MicroRNAs (miRNAs) are a member of non-coding RNA whose nucleotides range from 19 to 25. They are known to be critical regulators of cancer via epigenetic control of oncogenes expression and by regulating tumor suppressor genes. miRNAs have an essential function in a tumorous microenvironment via modulating cancer cell growth, metastasis, angiogenesis, metabolism, and apoptosis. Moreover, a wide range of information produced via several investigations indicates their tumor-suppressing, oncogenic, diagnostic assessment, and predictive marker functions in different types of lung malignancy. miRNA mimics or anti-miRNAs can be transferred into a lung cancer cell, with possible curative implications. As a result, miRNAs hold promise as targets for lung cancer treatment and detection. In this study, we investigate the different functions of various miRNAs in different types of lung malignancy, which have been achieved in recent years that show the lung cancer-associated regulation of miRNAs expression, concerning their function in lung cancer beginning, development, and resistance to chemotherapy, also the probability to utilize miRNAs as predictive biomarkers for therapy reaction.

Indexed as

Lung cancerMicroRNANSCLCSCLCTreatment

Identifiers

PMID37986065
PMCPMC10661689
OpenAlexW4388844038

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.