ArticlebioRxiv : the preprint server for biology2023
Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in
Liam C O'Connell, Victoria Johnson, Anika K Hutton, Jessica P Otis, Anastasia C Murthy, Mark C Liang, Szu-Huan Wang, Nicolas L Fawzi, Kimberly L Mowry
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors at 2 institutions in 1 country.
Liam C O'ConnellDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.
Victoria JohnsonDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.
Anika K HuttonDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.
Jessica P OtisDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.
Anastasia C MurthyDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.
Mark C LiangDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.
Szu-Huan WangDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.
Nicolas L FawziDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.ORCID 0000-0001-5483-0577 Kimberly L MowryDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University Providence, RI 02912, USA.ORCID 0000-0002-4126-2889 Brown University · USUniversity of California, Irvine · US
Funding
RNA Localization in Xenopus OocytesR01GM071049 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 2005 to 2018
$4.2MResidue-by-residue details of FUS protein phase separation and aggregationR01GM147677 · NIGMS · BROWN UNIVERSITY · PI FAWZI, NICOLAS LUX · 2022 to 2025
$1.7MNIGMS NIH HHS R01 GM071049NIGMS NIH HHS R01 GM147677
6 · The paper itselfAbstract
Proteins containing both intrinsically disordered regions (IDRs) and RNA binding domains (RBDs) can phase separate
Identifiers
PMID37986933
PMCPMC10659413
OpenAlexW4388559279
What Socratic holds
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