Evidence map›Paper›PMID 37990050›Full record

ReviewNPJ precision oncology2023

Radiological artificial intelligence - predicting personalized immunotherapy outcomes in lung cancer.

Laila C Roisman, Waleed Kian, Alaa Anoze, Vered Fuchs, Maria Spector, Roee Steiner, Levi Kassel, Gilad Rechnitzer, Iris Fried, Nir Peled and 1 more

Abstract readReview
In one paragraph

Review in NPJ precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  18. Personalized prediction of immunotherapy response in lung cancer patients using advanced radiomics and deep learning.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laila C Roisman *The Hebrew University, Helmsley Cancer Center, Shaare Zedek Medical Center, Jerusalem, Israel. dr.roisman@gmail.com.ORCID http://orcid.org/0000-0001-8455-9327
Waleed Kian *The Hebrew University, Helmsley Cancer Center, Shaare Zedek Medical Center, Jerusalem, Israel.
Alaa AnozeThe Hebrew University, Helmsley Cancer Center, Shaare Zedek Medical Center, Jerusalem, Israel.
Vered FuchsBen-Gurion University of the Negev, Be'er Sheva, Israel.
Maria SpectorThe Department of Radiology, Shaare Zedek Medical Center, Jerusalem, Israel.
Roee SteinerThe Institute for Nuclear Medicine, Shaare Zedek Medical Center, Jerusalem, Israel.
Levi KasselThe Hebrew University, Helmsley Cancer Center, Shaare Zedek Medical Center, Jerusalem, Israel.ORCID http://orcid.org/0000-0001-8607-0218
Gilad RechnitzerThe Hebrew University, Helmsley Cancer Center, Shaare Zedek Medical Center, Jerusalem, Israel.
Iris FriedThe Hebrew University, Helmsley Cancer Center, Shaare Zedek Medical Center, Jerusalem, Israel.
Nir PeledThe Hebrew University, Helmsley Cancer Center, Shaare Zedek Medical Center, Jerusalem, Israel. nirp@szmc.org.il.
Naama R BogotThe Department of Radiology, Shaare Zedek Medical Center, Jerusalem, Israel.

Funding

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101057695
6 · The paper itself

Abstract

Personalized medicine has revolutionized approaches to treatment in the field of lung cancer by enabling therapies to be specific to each patient. However, physicians encounter an immense number of challenges in providing the optimal treatment regimen for the individual given the sheer complexity of clinical aspects such as tumor molecular profile, tumor microenvironment, expected adverse events, acquired or inherent resistance mechanisms, the development of brain metastases, the limited availability of biomarkers and the choice of combination therapy. The integration of innovative next-generation technologies such as deep learning-a subset of machine learning-and radiomics has the potential to transform the field by supporting clinical decision making in cancer treatment and the delivery of precision therapies while integrating numerous clinical considerations. In this review, we present a brief explanation of the available technologies, the benefits of using these technologies in predicting immunotherapy response in lung cancer, and the expected future challenges in the context of precision medicine.

Identifiers

PMID37990050
PMCPMC10663598

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.