SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2023
Investigating the prognostic value of digital mobility outcomes in patients with chronic obstructive pulmonary disease: a systematic literature review and meta-analysis.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gait Speed and All-Cause Mortality in Whole-Spectrum Chronic Kidney Disease: A Systematic Review and Meta-Analysis Included 6217 Participants.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Gait differences between COPD and healthy controls: systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- The construct validity of real-world digital mobility outcomes in people with COPD.ERJ open research · 2026Article
- An open-source, externally validated neural network algorithm to recognize daily-life gait of older adults based on a lower-back sensor.Medical & biological engineering & computing · 2026Article
- Are Real-World Mobility Patterns Early Indicators of COPD Onset? Insights from Wrist-Worn Sensors.International journal of chronic obstructive pulmonary disease · 2026Article
- Pectoral muscle area derived from chest computed tomography to identify quadriceps muscle weakness in COPD.ERJ open research · 2025Article
- Association between income, employment status, and asthma outcomes: a systematic review and meta-analysis.The Lancet regional health. Europe · 2025Article
- A novel data-driven model to define physical activity metrics and predict mortality in patients with chronic obstructive pulmonary disease.Scientific reports · 2025Article
- How do people with COPD walk? A European study on digitally measured real-world gait.The European respiratory journal · 2025Article
- Cocreating the Visualization of Digital Mobility Outcomes: Delphi-Type Process With Patients.JMIR formative research · 2025Article
- Exploring the Causal Relationship Between Frailty and Chronic Obstructive Pulmonary Disease: Insights From Bidirectional Mendelian Randomization and Mediation Analysis.International journal of chronic obstructive pulmonary disease · 2025Article
- Walking pace and its association with osteoporosis and pathological fractures: insights from UK biobank.Frontiers in endocrinology · 2025Article
- Get a move on: physical (in)activity in people with obstructive airway disease.ERJ open research · 2024Article
- Prevalence and prognostic importance of exercise limitation and physical inactivity in COPD.Breathe (Sheffield, England) · 2024Review
- Combining Different Wearable Devices to Assess Gait Speed in Real-World Settings.Sensors (Basel, Switzerland) · 2024Article
- Article
- Modernisation of chronic respiratory disease management: The integration of wearable technology.Chronic respiratory diseaseReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReduced mobility is a central feature of COPD. Assessment of mobility outcomes that can be measured digitally (digital mobility outcomes (DMOs)) in daily life such as gait speed and steps per day is increasingly possible using devices such as pedometers and accelerometers, but the predictive value of these measures remains unclear in relation to key outcomes such as hospital admission and survival.
methodsWe conducted a systematic review, nested within a larger scoping review by the MOBILISE-D consortium, addressing DMOs in a range of chronic conditions. Qualitative and quantitative analysis considering steps per day and gait speed and their association with clinical outcomes in COPD patients was performed.
results21 studies (6076 participants) were included. Nine studies evaluated steps per day and 11 evaluated a measure reflecting gait speed in daily life. Negative associations were demonstrated between mortality risk and steps per day (per 1000 steps) (hazard ratio (HR) 0.81, 95% CI 0.75-0.88, p<0.001), gait speed (<0.80 m·s
conclusionDaily step count and gait speed are negatively associated with mortality risk and other important outcomes in people with COPD and therefore may have value as prognostic indicators in clinical trials, but the quantity and quality of evidence is limited. Larger studies with consistent methodologies are called for.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.